Progesterone Levels and Pregnancy Results

Pregnancy Complications Clinical Trial

Official title:

The Effect of Maternal Serum and Amniotic Fluid Progesterone Levels on Pregnancy Results

Clinical Trial Details — Status: Not yet recruiting

Administrative data

• NCT number: NCT04400149
• Other study ID #: amniotic fluid progesteron
• Status: Not yet recruiting
• Start date: December 1, 2021
• Est. completion date: November 20, 2022

Study information

• Verified date: October 2021
• Source: Ufuk University
• Contact: tufan arslanca, M.D.
• Phone: +905324580546
• Email: drtufanarslanca[@]hotmail.com
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

The aim of this study is to evaluate the amniotic fluid and serum progesterone level and pregnancy outcome

Description:

Studies have investigated the relationship between maternal serum progesterone level and low birth weight baby birth, hypertensive disorders of pregnancy, and early pregnancy bleeding. In some cases, patients are supported by oral or vaginal progesterone treatments during pregnancy. We also measure the relationship between maternal serum progesterone by measuring the level of amnion progesterone; We aimed to analyze the effects on pregnancy outcomes by observing preterm birth, premature rupture of membranes, low birth weight, baby gender, maternal problems that may occur during pregnancy, fetal problems.

Recruitment information / eligibility

• Status: Not yet recruiting
• Enrollment: 100
• Est. completion date: November 20, 2022
• Est. primary completion date: June 20, 2022
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Female
• Age group: 18 Years to 45 Years

Eligibility

Inclusion Criteria:

• Singleton pregnancy

• Women who did not receive progesterone treatment during pregnancy

Exclusion Criteria:

• Women who receive progesterone treatment during pregnancy

• multiple pregnancies

• Diagnosed hypertension, diabetes mellitus, kidney disease, heart disease, liver disease

Related Conditions & MeSH terms

• Pregnancy Complications
• Pregnancy Loss
• Pregnancy Preterm

Intervention

Diagnostic Test:
• amniocentesis
amniocentesis will be performed to the pregnant women at 16-20 weeks who had a high-risk antenatal test. Furthermore, these women also give a blood sample (at 16-20 weeks) to compare the amniotic fluid and serum progesterone levels in association with pregnancy outcomes. We perform amniocentesis to evaluate genetic disorders in pregnant women who had his risk in the antenal test.

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Ufuk University

References & Publications (2)

Johansson ED, Jonasson LE. Progesterone levels in amniotic fluid and plasma from women. I. Levels during normal pregnancy. Acta Obstet Gynecol Scand. 1971;50(4):339-43. — View Citation

Lau IF, Saksena SK, Salmonsen R. The concentration of progesterone, 20 alpha-dihydroprogesterone, testosterone, oestrone and oestradiol-17 beta in serum, amniotic fluid and placental tissue of pregnant rabbits. Acta Endocrinol (Copenh). 1982 Apr;99(4):605 — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	pregnancy outcome	premature membran rupture Web sonuçlari; Premature Rupture of Membranes	starting from 16 weeks, ending at the delivery of the baby
Primary	pregnancy outcome	pregnancy loss	starting from 16 weeks, ending at the delivery of the baby
Primary	pregnancy outcome	preeclampsia	starting from 16 weeks, ending at the delivery of the baby
Primary	pregnancy outcome	gestational diabetes	starting from 16 weeks, ending at the delivery of the baby
Secondary	fetal outcomes	low birth weight	starting from 16 weeks, ending at the delivery of the baby
Secondary	fetal outcomes	preterm labor	starting from 16 weeks, ending at the delivery of the baby
Secondary	fetal outcomes	fetal gender	starting from 16 weeks, ending at the delivery of the baby

External Links

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