Morning Light Treatment to Improve Glucose Metabolism — ML  

PreDiabetes Clinical Trial

Official title: Morning Light Treatment at Home to Improve Glucose Metabolism in People at Increased Risk for Type 2 Diabetes

Status Completed

Clinical Trial Summary

The primary purpose of this pilot study is to test a novel head worn light device (Re-Timer®) as an intervention to improve glucose metabolism in people with prediabetes. The hypothesis is that morning light treatment will improve glucose metabolism. This is a pilot study and the data from this project will be used to develop a larger clinical trial.

Clinical Trial Description

This is a pilot study to determine whether light treatment can improve glucose metabolism in people with prediabetes. Individuals will be asked to complete a baseline session with one-week of at-home sleep monitoring followed by a 24-hour stay in the clinical research unit. During this stay, we will sample saliva in the evening to measure melatonin to estimate the timing of the internal biological clock ("circadian phase") and then we will perform a 3-hour oral glucose tolerance test in the morning to estimate markers of glucose metabolism, including insulin sensitivity. The participants will then be given a light device and instructed on its use. They will use the device for four weeks and visit our laboratory every week for a check-in. At the end of the four weeks, they will repeat the 24-hour stay in the clinical research unit. ;

Related Conditions & MeSH terms

• Chronobiology Disorders
• Circadian Dysregulation
• PreDiabetes

• NCT number: NCT03188263
• Study type: Interventional
• Source: Northwestern University
• Status: Completed
• Phase: N/A
• Start date: September 5, 2017
• Completion date: December 31, 2019