Purification of Testis-Stimulating Factor in Precocious Puberty

Status Completed

Clinical Trial Summary

OBJECTIVES:

Purify and characterize a testis-stimulating factor in the blood of adult volunteers who had precocious puberty as boys.

Clinical Trial Description

PROTOCOL OUTLINE: Subjects are treated for 2 months with depot injections of leuprolide acetate every 4 weeks and testosterone replacement every 2 weeks. Hormone levels are tested every other week.

If luteinizing hormone and follicular-stimulating hormone levels are at or below detection on day 56, blood is drawn for a testis-stimulating factor bioassay and subsequent factor purification and characterization.

Volunteers are asked to repeat this 2-month procedure no more than 2 times every 12 months. ;

Study Design

Primary Purpose: Screening

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT00004344
Study type	Observational
Source	Office of Rare Diseases (ORD)
Contact
Status	Completed
Phase	N/A
Start date	January 1997

View Details

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