Precancerous Condition Clinical Trial
Official title:
Phase II Study of Immunotherapy With Autogenous Papilloma Vaccine in Patients With Recurrent Juvenile Papilloma of the Larynx
RATIONALE: Vaccines made from papilloma virus cells may make the body build an immune
response to and kill papilloma cells.
PURPOSE: Phase II trial to study the effectiveness of papilloma virus vaccine in treating
young patients with recurrent papilloma of the larynx.
OBJECTIVES: I. Determine the immune response in patients with juvenile papilloma of the
larynx treated with autogenous vaccine derived from each patient's own tumor.
OUTLINE: Patients receive autogenous papilloma vaccine intradermally and subcutaneously
weekly for 20 weeks.
PROJECTED ACCRUAL: Not specified
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