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Angiogenesis Markers in Primiparas Versus Multiparas: Relevance to Preeclampsia Incidence

Pre-Eclampsia Clinical Trial

Official title:
Angiogenesis Markers in Primiparas Versus Multiparas: Relevance to Preeclampsia Incidence

Clinical Trial Summary

The reason for having a higher incidence of preeclampsia in primiparas may involve angiogenesis imbalance in these patients.

Clinical Trial Description

Primiparity is one of the main risk factors for having preeclampsia during pregnancy. Recently, sFlt-1, soluble FMS-like tyrosine kinase-1, has been shown to be a major molecule involved in the pathogenesis of preeclampsia. Higher sFlt-1 mRNA, higher serum levels of sFlt-1 as well as lower PlGF, placental growth factor, have been found in preeclamptic patients.

We intend to check the angiogenesis profile of primiparas as compared to multiparas. ;

Study Design

Observational Model: Case Control, Primary Purpose: Screening, Time Perspective: Cross-Sectional

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT00262093
Study type Observational
Source Hadassah Medical Organization
Contact Yuval Bdolah, MD, MSc
Phone 972-2-5844111
Email ybdolah@hadassah.org.il
Status Recruiting
Phase N/A
Start date November 2005
View Details
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