Bioavailability of Anthocyanins of Blue Potatoes as Compared With Bilberries

Postprandial Glycemia Clinical Trial

Official title:

Bioavailability of Anthocyanins of Blue Potatoes as Compared With Bilberries

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT02005796
• Other study ID #: Siniset perunat
• Status: Completed
• Phase: N/A
• First received: December 3, 2013
• Last updated: May 19, 2015
• Start date: December 2013
• Est. completion date: May 2015

Study information

• Verified date: May 2015
• Source: University of Turku
• Contact: n/a
• Is FDA regulated: No
• Health authority: Finland: Ministry of Social Affairs and Health
• Study type: Interventional

Clinical Trial Summary

In this study, the postprandial glycemia and insulinemia caused by boiled potato with blue-fleshed or yellow-fleshed tubers, or a gel prepared with bilberries and potato starch, is studied in healthy males. Additionally, the appearance and metabolism of the flavonoids and their metabolites is studied in plasma and urine.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 14
• Est. completion date: May 2015
• Est. primary completion date: May 2015
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Male
• Age group: 18 Years to 45 Years

Eligibility

Inclusion Criteria:

• Age 18-45

• Male

• No regular medication

• No participation in a drug trial or blood donation within 2 months

• Non-smoker

• Signs informed consent

• Body mass index 18.5-27 kg/m2

• Fasting plasma cholesterol < 5.5 mmol/l

• Fasting plasma triacylglycerols < 2.6 mmol/l

• Fasting plasma glucose 4-6 mmol/l

• blood pressure <140/80 mmHg

• hemoglobin>130 g/l

• Fasting plasma alanine amino transferase (ALAT) <60 U/l (normal liver function)

• Fasting plasma thyroid-stimulating hormone (TSH) 0.4 - 4.5 mU/l (normal thyroid function)

• Fasting plasma creatinine <118 µmol/l (normal kidney function)

Exclusion Criteria:

• Regular smoking

• Alcohol abuse

• Regular medication

Study Design

Allocation: Randomized, Intervention Model: Crossover Assignment, Masking: Single Blind (Investigator), Primary Purpose: Basic Science

Related Conditions & MeSH terms

• Postprandial Glycemia

Intervention

Other:
• Dietary intervention

Locations

Country	Name	City	State
Finland	Department of Biochemistry, University of Turku	University of Turku	Turku

Sponsors (1)

Lead Sponsor	Collaborator
University of Turku

Country where clinical trial is conducted

Finland, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Plasma glucose concentration		20min, 40min, 60min, 90min, 120min, 180min, 240min	No
Primary	Plasma insulin concentration		20min, 40min, 60min, 90min, 120min, 180min, 240min	No
Secondary	Concentrations and quality of flavonoid color compounds or their metabolites in plasma and urine (HPLC-measurement)		20min, 40min, 60min, 90min, 120min, 180min, 240min	No
Secondary	Concentrations and quality of flavonoid color compounds or their metabolites in plasma and urine (NMR-measurement)		20min, 40min, 60min, 90min, 120min, 180min, 240min	No