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Fever After Misoprostol Administration for the Treatment of Primary Postpartum Hemorrhage

Postpartum Hemorrhage Clinical Trial

Official title:
Assessment of Fever After Misoprostol Administration for the Treatment of Primary Postpartum Hemorrhage

Clinical Trial Summary

This study will evaluate side effects after sublingual misoprostol (600 mcg) as a first-line treatment for primary postpartum hemorrhage (PPH) due to suspected uterine atony.

Clinical Trial Description

The study purpose is to confirm whether a lower, 600 mcg dose of sublingual misoprostol will reduce the incidence of elevated body temperature (≥40°C) associated with misoprostol. The study will compare the incidence of high fevers following treatment with 600 mcg sublingual misoprostol to previously documented rates using 800 mcg sublingual misoprostol. An additional line of research is to investigate whether some women are more susceptible to experiencing high fevers following misoprostol administration, and whether genetic factors are responsible for misoprostol-induced fevers. ;

Study Design

Endpoint Classification: Safety Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01080846
Study type Interventional
Source Gynuity Health Projects
Contact
Status Completed
Phase N/A
Start date February 2010
Completion date August 2010
View Details
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