Effect of Colding of Endotracheal Tubes on Sore Throat

Status Recruiting

Clinical Trial Summary

Postoperative sore throat (POST) is a common and undesirable postoperative symptom that causes patient dissatisfaction. Cold application is a non-invasive, non-pharmacological, cost-effective and effort-effective therapy for pain management. The aim of this study was to evaluate whether colding of ETT can reduce sore throat, dysphagia and dysphonia after endotracheal intubation.

Clinical Trial Description

The incidence of postoperative sore throat (POST) has been reported up to 62% following general anaesthesia.It is an undesirable events experienced by patients after general anaesthesia. Various pharmacological agents have been applied to reduce POST, such as lidocaine, ketamine, magnesium, corticosteroids or non-steroidal anti-inflammatory drugs. However, these agents may have some systemic and local side effects. Therefore, various non-pharmacological applications have been investigated to reduce sore throat. Cold application is a non-invasive, cost-effective and effort-effective therapy for pain management. Although the mechanism is not clearly known, it increases the pain threshold, slows cellular metabolism, causes vasoconstriction, and reduces capillary permeability. Therefore, we hypothesized that colding of endotracheal tube may decrease POST associated with airway inflammation. The aim of this study was to evaluate whether colding of ETT can reduce sore throat, dysphagia and dysphonia after endotracheal intubation. The goal of this study is to identify a simple, safe, and inexpensive perioperative intervention to reduce post operative sore throat. This study is a prospective, randomised study involving 116 subjects and they will assessed on the incidence and severity of sore throat, dysphagia and dysphonia at 1. 4. 12. 24. hours after removal of endotracheal tube. Outcomes from this study can be extended to patients who will be receiving general anaesthesia using a endotracheal tube to reduce the incidence and severity of sore throat. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT05834179
Study type	Interventional
Source	Baskent University
Contact	sibel çatalca, dr.
Phone	90 322 327 27 27
Email	drsibelcatalca@gmail.com
Status	Recruiting
Phase	N/A
Start date	March 15, 2023
Completion date	May 7, 2023

View Details

See also
Status	Clinical Trial	Phase
Enrolling by invitation	`NCT03885752` - The Effects of Preoperatively Chewing Gum on Sore Throat After General Anaesthesia With a Laryngeal Mask	Phase 1/Phase 2
Recruiting	`NCT06266481` - Topical Dexamethasone Versus Topical Lidocaine Spray to Reduce POST in Shoulder Arthroscopic Surgeries: A Comparative Study	Phase 2/Phase 3
Recruiting	`NCT05436743` - Efficacy of K-Y Jelly in Prevention of Postoperative Sore Throat After Nasal Surgery	Phase 4
Recruiting	`NCT06218836` - Effect of Inflated Versus Non-inflated Endotracheal Tube on Sore Throat	N/A
Not yet recruiting	`NCT03792776` - Effect of Lidocaine 1% and 2% in the Tube Cuff on Postoperative Sore Throat and Cough	N/A
Completed	`NCT04371094` - Sore Throat After Intubation Using Glidescope With Stylet and Bougie	N/A
Enrolling by invitation	`NCT04644900` - Effect of Chewing Gum and Mouthwash Before Operation on Sore Throat After General Anesthesia With a Laryngeal Mask	N/A
Active, not recruiting	`NCT06122324` - Effect of Lidocaine on Hemodynamic Response and Postoperative Sore Throat
Completed	`NCT02492646` - Effect of Saline Lubrication on Post-intubation Complications	N/A
Recruiting	`NCT05825872` - Ultrasound-Guided Internal Superior Laryngeal Nerve Block for Double-Lumen Bronchial Tube	Phase 4
Not yet recruiting	`NCT06368843` - the Impact of Ketamine Gargling on the Incidence of Post Intubation Sore Throat

Clinical trials are conducted in a series of steps, called phases - each phase is designed to answer a separate research question.

Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.