Clinical Trials Logo

Clinical Trial Details — Status: Not yet recruiting

Administrative data

NCT number NCT06205719
Other study ID # 2023-234-1
Secondary ID
Status Not yet recruiting
Phase Early Phase 1
First received
Last updated
Start date June 1, 2024
Est. completion date May 30, 2026

Study information

Verified date May 2024
Source Sichuan Provincial People's Hospital
Contact YanYu Liu
Phone 13438348895
Email 43197113@qq.com
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

to investigate the effect of remazolam benzenesulfonate in patients with ocular fundus surgery, so as to guide clinical anesthesiologists to choose more appropriate anesthetic drugs in fundus surgery


Description:

to investigate the effect of remazolam benzenesulfonate in patients with ocular fundus surgery, so as to guide clinical anesthesiologists to choose more appropriate anesthetic drugs in fundus surgery。There are three groups.In Group H, ciprofol + Remifentanil was used for maintenance of anesthesia, in Group R, remifentanil + Remifentanil was used for maintenance of anesthesia, in Group RF, remifentanil + Remifentanil was used for maintenance of anesthesia, at the end of the operation, flumazenil was used to counteract the residual anesthetic effect.The quality of postoperative recovery was compared


Recruitment information / eligibility

Status Not yet recruiting
Enrollment 93
Est. completion date May 30, 2026
Est. primary completion date May 30, 2025
Accepts healthy volunteers No
Gender All
Age group 18 Years to 65 Years
Eligibility Inclusion Criteria: 1. ASA I-II, patients 2. aged 18-65 years old; 3. Fundus surgery to be performed under general anesthesia ; 4. The expected duration of surgery is about 30-120 min ; 5. BMI: 18-30 kg/m2 ; 6. Those who signed the informed consent form and volunteered to participate in this trial Exclusion Criteria: 1. Patients with known or suspected genetic susceptibility to malignant hyperthermia; 2. Patients with history of asthma; 3. Patients with severe heart diseases (NYHA = III, severe arrhythmia, etc.) and cerebral or pulmonary diseases, liver or kidney dysfunction; or with unstable vital signs; 4. Patients with history of long-term narcotic analgesics application, including sedative and antidepressant drugs; 5. Patients with history of psychotropic drug abuse within 3 months; 6. Patients with long-term alcohol abuse; 7. People with mental disorder and unable to communicate normally;

Study Design


Related Conditions & MeSH terms


Intervention

Drug:
ciprofol
sedation
Remazolam
sedation
Flumazenil
antagonism
Remifentanil
2ug/kg Remifentanil

Locations

Country Name City State
n/a

Sponsors (1)

Lead Sponsor Collaborator
Sichuan Provincial People's Hospital

Outcome

Type Measure Description Time frame Safety issue
Primary time for recovery The time from stopping the anesthetic to waking up 3 second to 30minutes
See also
  Status Clinical Trial Phase
Recruiting NCT05255120 - Hysterectomy - A Regional Intervention Study N/A
Completed NCT04112394 - Does Erector Spinal Block Improve Quality of Recovery After Laparoscopic Cholecystectomy N/A
Not yet recruiting NCT02534623 - Postoperative Quality of Recovery After Transurethral Resection of the Bladder N/A
Completed NCT02141412 - Intravenous Dexmedetomidine For The Quaity Of Emergence From General Anesthesia Phase 4
Not yet recruiting NCT05450172 - Impact of Postoperative Transitional Pain on Recovery After Thoracic Surgery
Not yet recruiting NCT06469515 - Older People's Neurocognitive Recovery After Cardiac Surgery
Not yet recruiting NCT04733703 - Impact of Postanesthesia Care Unit Delirium on Postoperative Quality of Recovery
Completed NCT05361460 - Patients Experiences of Early Postoperative Cognition
Recruiting NCT05596695 - Minimisation of Blood Pressure Variability and Postoperative Nausea and Vomiting N/A
Active, not recruiting NCT05603364 - Effect of Postoperative Oral Carbohydrate Administration in Total Knee Arthroplasty Elderly Patients Early Phase 1
Completed NCT02921529 - TEAS Enhanced Recovery After Laparoscopic Colon Surgery N/A
Recruiting NCT06347770 - Effect of Probiotics Before Cesarean Section on Postoperative Recovery in Pregnant Women N/A
Not yet recruiting NCT05867264 - Effect of Early Postoperative Oral Carbohydrate on Postoperative Recovery of the Unilateral Knee Arthroplasty Early Phase 1
Recruiting NCT05879536 - The Effect of Intravenous Infusion of Tramadol-ondansetron on Recovery After Caesarean Section.
Recruiting NCT05843383 - Comparison of Ciprofol-based and Propofol-based Total Intravenous Anesthesia on Postoperative Quality of Recovery N/A
Completed NCT05331027 - The Effect of Desflurane Versus Sevoflurane on Postoperative Recovery Phase 4
Not yet recruiting NCT03249701 - Electrical Acupoint Stimulation for Postoperative Recovery N/A
Recruiting NCT06305221 - Effect of Opioid-free Analgesia and Anesthesia on the Quality of Postoperative Recovery and Nausea Vomit in Patients Receiving Laparoscopic Sleeve Gastrectomy N/A
Recruiting NCT06341049 - Effect of Three Different Postcesarean Analgesic Techniques on QbsQor-10 Score: Prospective, Randomized Trial N/A
Completed NCT04304274 - Programmed Intermittent Bolus Infusion of Thoracic Paravertebral Block for Hepatectomy N/A