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Postoperative Pain clinical trials

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NCT ID: NCT02660918 Completed - Postoperative Pain Clinical Trials

Decreasing Postoperative Pain Following Endometrial Ablation

Start date: April 2016
Phase: N/A
Study type: Interventional

To determine whether paracervical injection of long acting local anesthesia decreases postoperative pain following endometrial ablation under general anesthesia.

NCT ID: NCT02658240 Completed - Postoperative Pain Clinical Trials

Ultrasound-guided Fascia Iliaca Compartment Block Versus Periarticular Infiltration

Start date: April 5, 2016
Phase: N/A
Study type: Interventional

This randomized, controlled, observer-blinded study clinical trial was designed to evaluate ultrasound-guided fascia iliaca compartment block with ropivacaine and periarticular infiltration with ropivacaine for postoperative pain management after total hip arthroplasty.

NCT ID: NCT02653651 Completed - Postoperative Pain Clinical Trials

Effects of Perioperative Intravenous Lidocaine and Ketamine on Acute and Chronic Pain After Open Nephrectomy

Start date: January 2016
Phase: Phase 4
Study type: Interventional

Open nephrectomy is one of the most common surgical procedures in urologic practice. Pain after surgery remains a significant clinical problem as it impairs recovery adversely and may lead to the transition to chronic pain. The open approach represents a major physical trauma including postoperative pain and discomfort in the convalescence period. Adequate control of postoperative pain facilitates earlier mobilization and rehabilitation. Patient-controlled analgesia (PCA) is effective to treat pain at rest, but seems to be inadequate for dynamic analgesia and may also elicit side effects that may delay hospital discharge. Preventing early and late postsurgical pain is an important challenge for anesthesiologists and surgeons. Ketamine (N-Methyl-D-Aspartate receptor antagonist) and lidocaine (sodium channel blocker) are popular analgesic adjuvants for improving perioperative pain management. The investigators designed this double-blind, placebo controlled study to test and compare the preventive effects of perioperative intravenous ketamine and lidocaine on early and chronic pain after elective open nephrectomy. The investigators propose a double-blind placebo-controlled study of patients undergoing elective open nephrectomy. All patients will receive normal "patient-controlled analgesia morphine" in addition to study drugs or placebo. Research will be conducted at Charles Nicolle teaching hospital.

NCT ID: NCT02649179 Completed - Postoperative Pain Clinical Trials

Local Infiltration With Ropivacaine Improves Postoperative Pain Control in Patients

Start date: August 2016
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the effect of pain relief after infusion of ropivacaine at port sites at end of laparoscopic cholecystectomy (LC)compared with placebo (0.9% normal saline).

NCT ID: NCT02643394 Completed - Postoperative Pain Clinical Trials

Efficacy of Oral vs. Intravenous Acetaminophen

Start date: August 17, 2015
Phase: Phase 4
Study type: Interventional

The comparative efficacy of intravenous (IV) to oral (PO-'per os') acetaminophen in the management of postoperative pain is understudied and largely unknown. In this observer blinded randomized clinical trial, investigators aim to determine the comparative efficacy of PO (preoperative) vs. IV (intraoperative) acetaminophen in a sinus surgery population.

NCT ID: NCT02642796 Completed - Postoperative Pain Clinical Trials

Transcutaneous Nerve Stimulation for Post-operative Acute and Chronic Pain

Start date: March 2013
Phase: N/A
Study type: Interventional

Aim of the study to assess the efficacy of two modes of transcutaneous electrical nerve stimulation (TENS) on relief of postoperative acute pain after hip fracture surgery.

NCT ID: NCT02642497 Completed - Postoperative Pain Clinical Trials

Local Ketamine Instillation for Postoperative Analgesia

Start date: August 2015
Phase: Phase 2/Phase 3
Study type: Interventional

This study aims at exploring the analgesic efficacy, and safety of Ketamine instillation into the wound of total thyroidectomy compared to placebo,and to systemic ketamine administration (I.M. injection of the same dose) with respect to postoperative VAS, first request of analgesia, total opioid consumption, and with respect to possible side effects.

NCT ID: NCT02639741 Completed - Postoperative Pain Clinical Trials

Preoperative Melatonin or Vitamin C Administration on Postoperative Analgesia

Start date: November 2014
Phase: Phase 4
Study type: Interventional

The investigators designed a randomized double-blind placebo-controlled trial to evaluate the effect of preoperative single dose of oral melatonin and vitamin C administration on postoperative analgesia in patients undergoing elective major abdominal surgery.

NCT ID: NCT02619799 Completed - Postoperative Pain Clinical Trials

A Comparative Study of Intrathecal Magnesium Sulphate & Midazolam With Epidural Ropivacaine for Caesarean Patients

Start date: January 2015
Phase: Phase 2/Phase 3
Study type: Interventional

This study compares whether addition of Magnesium or Midazolam intrathecally to epidurally administered isobaric Ropivacaine improves the quality of blockade, haemodynamics and duration of analgesia post-operatively. 25 parturients were given intrathecal Magnesium and rest of the 25 parturients were given intrathecal Midazolam combined with 0.75% Ropivacaine via epidural route.

NCT ID: NCT02619032 Completed - Postoperative Pain Clinical Trials

Remifentanil and Fentanyl in Dental Surgery (REFEDS)

REFEDS
Start date: October 2005
Phase: N/A
Study type: Interventional

This study was a prospective comparative study. The purpose of this study was to investigate the hypothesis whether remifentanil compared to fentanyl can induce less inflammatory and stress response to the day-case dental surgery in Persons with special needs (PSN). Secondary aims were to investigate comparatively their effect on patients intraoperative hemodynamic response and postoperative analgesia.