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Postoperative Pain clinical trials

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NCT ID: NCT02642497 Completed - Postoperative Pain Clinical Trials

Local Ketamine Instillation for Postoperative Analgesia

Start date: August 2015
Phase: Phase 2/Phase 3
Study type: Interventional

This study aims at exploring the analgesic efficacy, and safety of Ketamine instillation into the wound of total thyroidectomy compared to placebo,and to systemic ketamine administration (I.M. injection of the same dose) with respect to postoperative VAS, first request of analgesia, total opioid consumption, and with respect to possible side effects.

NCT ID: NCT02639741 Completed - Postoperative Pain Clinical Trials

Preoperative Melatonin or Vitamin C Administration on Postoperative Analgesia

Start date: November 2014
Phase: Phase 4
Study type: Interventional

The investigators designed a randomized double-blind placebo-controlled trial to evaluate the effect of preoperative single dose of oral melatonin and vitamin C administration on postoperative analgesia in patients undergoing elective major abdominal surgery.

NCT ID: NCT02619799 Completed - Postoperative Pain Clinical Trials

A Comparative Study of Intrathecal Magnesium Sulphate & Midazolam With Epidural Ropivacaine for Caesarean Patients

Start date: January 2015
Phase: Phase 2/Phase 3
Study type: Interventional

This study compares whether addition of Magnesium or Midazolam intrathecally to epidurally administered isobaric Ropivacaine improves the quality of blockade, haemodynamics and duration of analgesia post-operatively. 25 parturients were given intrathecal Magnesium and rest of the 25 parturients were given intrathecal Midazolam combined with 0.75% Ropivacaine via epidural route.

NCT ID: NCT02619032 Completed - Postoperative Pain Clinical Trials

Remifentanil and Fentanyl in Dental Surgery (REFEDS)

REFEDS
Start date: October 2005
Phase: N/A
Study type: Interventional

This study was a prospective comparative study. The purpose of this study was to investigate the hypothesis whether remifentanil compared to fentanyl can induce less inflammatory and stress response to the day-case dental surgery in Persons with special needs (PSN). Secondary aims were to investigate comparatively their effect on patients intraoperative hemodynamic response and postoperative analgesia.

NCT ID: NCT02618876 Completed - Postoperative Pain Clinical Trials

Effect of Caudal Nalbuphine on Postoperative Analgesia in Children

Start date: November 2015
Phase: N/A
Study type: Interventional

Nalbuphine as an adjuvant to bupivacaine caudal anesthesia for postoperative analgesia in children undergoing Hypospadias repair. 2 groups, 30 patients each

NCT ID: NCT02605187 Completed - Postoperative Pain Clinical Trials

Patient-Driven Analgesic Protocol Selection for Post-Cesarean Pain Management

Start date: November 2015
Phase: N/A
Study type: Interventional

The ability to predict pain and then apply modified treatment protocols has been limited. Current practice is for physicians to select standard post-operative pain treatment protocols without patient consultation. This study hopes to determine if patient's involvement in analgesic drug/dosage selection can optimize pain relief while minimizing related side effects. This could result in a more patient-centered care model and individualized perioperative analgesic treatment protocols based on patient's preferences, needs and expectations.

NCT ID: NCT02602197 Active, not recruiting - Postoperative Pain Clinical Trials

Intravenous Paracetamol Compared Dexketoprofen for Postoperative Analgesia After Septoplasty

Start date: August 2013
Phase: Phase 3
Study type: Interventional

The investigators conducted a prospective, randomized, double blind study to compare the effectiveness of intravenous paracetamol and dexketoprofen for preventing pain during first 24 hours postoperative period in adult patient undergoing septoplasty.

NCT ID: NCT02592460 Completed - Postoperative Pain Clinical Trials

Postoperative Pain and Polyamines-poor Diet (DOLAMINE)

DOLAMINE
Start date: December 2014
Phase: N/A
Study type: Interventional

Animal studies have shown that the level of pain sensitivity is highly dependent on the amount of polyamines in food. This fundamental observation of a nutritional approach to pain led the authors to develop diets completely depleted in polyamines whose anti-nociceptive properties have been confirmed in animals. Postoperative pain after foot surgery are currently fairly well controlled but at the cost of a high consumption of grade II analgesics which is associated with a high rate of side effects (nausea, vomiting ...). The investigators' hypothesis is that a diet low in polyamines may have an additive effect on pain control and reduce the consumption of level 2 analgesics. The objective of this study is to show the efficacy of a polyamines-poor diet on postoperative pain in ambulatory surgery of the foot.

NCT ID: NCT02589834 Completed - Postoperative Pain Clinical Trials

The Effect of Quran of Post Operative Pain

Start date: April 2015
Phase: Phase 2
Study type: Interventional

Postoperative pain management is crucial for surgical patients. Management of postoperative pain entails reducing painful symptoms, improving the quality of recovery and resuming normal daily living activities. In addition to the benefits derived from relieving postoperative pain in women undergoing cesarean section, prolonged immobility as a result of pain during puerperium is associated with risk of thromboembolic disease. Postoperative pain has negative physiological and psychological impact on patients' well-beings and delays the postoperative recovery. Pain may also impair the mother's ability to provide an optimal care for her infant in the immediate postpartum period. Besides that, it also reduces the maternal ability to breast-feed her infant effectively. Effective pain relief should not interfere with the mother's ability to move around and care for her infant, and that it results in no adverse neonatal effects in breast-feeding women. Non-pharmacological techniques for reduction of pain are growing rapidly. Spiritual intervention with listening to Quran recitations as an adjunctive therapy in the postoperative period is a non-pharmacological technique that is inexpensive, non-invasive and has no side-effects. Spiritual and Islamic implication could improve postoperative pain 6-8 hours and 24-30 hours in Muslim patients undergoing abdominal surgery. However, there is limited number of published studies on the effect of spiritual and religious intervention on pain after cesarean section. Listening to Quran recitation elicits a relaxation response of calmness, mindfulness, and peacefulness in Muslims. Pray therapy results in optimal harmonization, which improves psychological, social, spiritual, and physical health status. The current study aims to investigate the effects of listening to Quran recitation on pain intensity among patients after cesarean section according to the cultural, social and economic differences in Egypt.

NCT ID: NCT02581566 Completed - Postoperative Pain Clinical Trials

Effect of Intrathecal vs Intraarticular Dexmedetomidine on Postoperative Pain Following Arthroscopy

Start date: July 2015
Phase: N/A
Study type: Interventional

Comparison between intrathecal Dexmedetomidine versus Intraarticular Dexmedetomidine on postoperative pain after knee arthroscopy.