Postoperative CRP Levels and Vaginal Cuff Hematoma

Postoperative Hematoma Clinical Trial

Official title:

The Value of Postoperative CRP Levels to Predict Postoperative Vaginal Cuff Hematoma

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03879499
• Other study ID #: 2017/78
• Status: Completed
• Start date: January 1, 2017
• Est. completion date: January 1, 2018

Study information

• Verified date: March 2019
• Source: Kanuni Sultan Suleyman Training and Research Hospital
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

After laparoscopic hysterectomy, authors aimed to determine cuff hematoma and a postoperative CRP value to help predict the other complications.

A total of 136 patients who underwent total laparoscopic hysterectomy (TLH) were evaluated. CRP, White blood cell (WBC) and hemoglobin values (Hb) were measured on the 1st, 2nd and 7th days before and after the operation. Complications, pre-postoperative vaginal length and female sexual function were evaluated. Fourteen patients who developed cuff hematoma during postoperative follow-up were analyzed with the receiver operating characteristics (ROC) curve. ROC curves with the largest area under the curve for each inflammatory marker were compared in order to define the marker with higher diagnostic accuracy.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 106
• Est. completion date: January 1, 2018
• Est. primary completion date: January 1, 2018
• Accepts healthy volunteers: No
• Gender: Female
• Age group: N/A and older

Eligibility

Inclusion Criteria:women who underwent TLH operation with benign gynecological indications

Exclusion Criteria:

• Decided to switch to laparotomy during operation

• postoperative complication due to relaparotomy

• infection (including urinary system and lung infections)

• Blood transfusion after TLH

• with rheumatic diseases

• length of hospital stay due to wound infection

Related Conditions & MeSH terms

• Hematoma
• Postoperative Hematoma

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Kanuni Sultan Suleyman Training and Research Hospital

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Relationship between CRP Levels and cuff hematoma; crp levels	The value of Postoperative CRP Levels to predict Postoperative Vaginal Cuff Hematoma ; To evaluate tissue trauma and surgical inflammatory responses, venous peripheral blood samples (C-reactive protein) were taken on the first, second and seventh day postoperatively. CRP values were measured under standardized conditions using turbidometry. CRP levels (mg / dl) were recorded.	1 week
Primary	Relationship between CRP Levels and cuff hematoma; cuff hematoma measurement	The patients were called to the outpatient clinic after the hysterectomy and evaluated by transvaginal ultrasonography (tvusg) for cuff hematoma.hematoma dimensions recorded in centimeters.	15 days