Postoperative Delirium Clinical Trial
Official title:
Effects of Perioperative Operating Room Environment on Postoperative Delirium in Elderly Patients With Abdominal Surgery : A Prospective Cohort Study
Thi investigators aims to observe the impact of perioperative body temperature and the noise of operating room on postoperative delirium for elderly patients undergoing abdominal surgery. And based on this study the investigators aimed to explore the potential risk factors of postoperative delirium for elderly patients undergoing abdominal surgery.
Status | Recruiting |
Enrollment | 360 |
Est. completion date | February 26, 2024 |
Est. primary completion date | December 30, 2023 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 65 Years to 90 Years |
Eligibility | Inclusion Criteria: - Age 65-90 years old; - ASA I-III; - Patients who plan to undergo elective abdominal surgery under general anesthesia; - Volunteer to participate in this study and sign informed consent. Exclusion Criteria: - Patients with known mental illness or lack of communication or cognitive impairment before operation; - Severe vision, hearing, language impairment or other reasons unable to communicate with visitors; - Severe dysfunction of important organs such as heart, brain, lung, liver, kidney, etc.; - Long-term use of sedatives, antidepressants or alcoholism; - Patients with severe postoperative complications and admitted to intensive care unit; - Patients who refused or failed to complete the cognitive function test. - Patients who could not cooperate with the study for any other reason. |
Country | Name | City | State |
---|---|---|---|
China | Department of Anesthesiology, The Second Affiliated Hospital, Chongqing Medical University | Chongqing | Chongqing |
Lead Sponsor | Collaborator |
---|---|
The Second Affiliated Hospital of Chongqing Medical University |
China,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Postoperative delirium during the 3 days-follow-up after anesthetic resuscitation | Postoperative delirium was tested with 3 minutes-Confusion Assessment Method or Confusion Assessment Method-intensive care unit (0-4, higher scores means worse outcome). The patient is determined to be postoperative delirium (ie, Confusion Assessment Method positive) if he/she fall ill quickly with confusion disorder, and with mental disorder or consciousness disorder. | From ending of the surgery to 3 days after anesthetic resuscitation | |
Secondary | Postoperative delirium in the postanesthesia care unit | Postoperative delirium was tested with 3 minutes-Confusion Assessment Method (0-4, higher scores means worse outcome). The patient is determined to be postoperative delirium (ie, Confusion Assessment Method positive) if he/she fall ill quickly with confusion disorder, and with mental disorder or consciousness disorder. | From ending of the surgery to the time when discharge from postanesthesia care unit, an average of 30 minutes | |
Secondary | Hospital stay | Time duration of the patients' stay in hospital | From the ending of the surgery to hospital discharge, with means of about 7 days | |
Secondary | Postoperative complication | The number of patients who having complication during the hospitalization | From the ending of the surgery to hospital discharge, with means of about 7 days |
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT03606941 -
Effect of Electroacupuncture on the Incidence of Postoperative Delirium in Elderly Patients Undergoing the Major Surgery
|
N/A | |
Recruiting |
NCT05990790 -
The Effect of Desflurane Versus Sevoflurane Versus Propofol on Postoperative Delirium
|
Phase 4 | |
Completed |
NCT03950440 -
Assessing the Incidence of Postoperative Delirium Following Aortic Valve Replacement
|
||
Terminated |
NCT03337282 -
Incidence and Characteristics of Postoperative Cognitive Dysfunction in Elderly Quebec Francophone Patients
|
||
Completed |
NCT02585128 -
Predictors of Postoperative Delirium After Transcatheter Aortic Valve Implantation
|
N/A | |
Recruiting |
NCT02227225 -
Factors Affecting the Incidence of Postoperative Delirium in Frail Elderly
|
N/A | |
Recruiting |
NCT01934049 -
Postoperative Recovery in Elderly Patients Undergoing Hip Hemi-arthroplasty
|
Phase 4 | |
Terminated |
NCT00455143 -
Cognitive Protection - Dexmedetomidine and Cognitive Reserve
|
Phase 4 | |
Recruiting |
NCT05010148 -
A Clinical Trial of Intravenous Lidocaine After Spinal Surgery to Prevent Delirium and Reduce Pain
|
Phase 3 | |
Completed |
NCT06178835 -
EPO for Postop Delirium in Elderly Patients
|
Phase 4 | |
Recruiting |
NCT05992506 -
Electroencephalographic Biomarker to Predict Postoperative Delirium
|
||
Recruiting |
NCT03839784 -
Building a Platform for Precision Anesthesia in the Geriatric Surgical Patient
|
||
Completed |
NCT04154176 -
Validation of the Greek Version of the Confusion Assessment Method Diagnostic Algorithm (CAM) and the Nursing Delirium Screening Scale (Nu-DESC) and Their Inter-rater Reliablity
|
||
Not yet recruiting |
NCT06375265 -
Digital Sleep Optimization for Brain Health Outcomes in Older Surgical Patients
|
N/A | |
Recruiting |
NCT05572307 -
Peripheral Blood Single Cell Sequencing Analysis of POD and CPSP in Elderly Patients After Total Knee Arthroplasty
|
||
Active, not recruiting |
NCT03629262 -
Dexmedetomidine Supplemented Intravenous Analgesia in Elderly After Orthopedic Surgery
|
Phase 4 | |
Not yet recruiting |
NCT05537155 -
Buccal Acupuncture for Delirium Treatment in Older Patients Recovering From Orthopedic Surgery
|
N/A | |
Completed |
NCT01964274 -
Relevance of the Peripheral Cholinesterase-activity on Neurocognitive Dysfunctions in Surgical Patients
|
||
Completed |
NCT01599689 -
Pilot and Feasibility Study of a Mirrors Intervention for Reducing Delirium in Older Cardiac Surgical Patients
|
N/A | |
Active, not recruiting |
NCT03291626 -
Postoperative Delirium: EEG Markers of Sleep and Wakefulness
|