Postoperative Delirium Clinical Trial
Official title:
Treatment of Postoperative Delirium With Continuous Theta Burst Stimulation: an Exploratory Study
To determine whether continuous theta burst stimulation can cure postoperative delirium in senior patients.
Postoperative delirium(POD), a syndrome characterized by an acute change in attention, awareness and cognition, is one of the most common postoperative complications among elderly patients. Impaired neuronal network connectivity is likely one of the several neurobiological processes that contribute to POD pathogenesis. Recently, continuous theta burst stimulation (cTBS) was demonstrated to improve cognitive function in patients with mild cognitive impairment.Recent research suggests that cTBS has positive effect on improving the connectivity and reorganization of the brain network. Therefore, we plan to conduct an exploratory study in participants undergoing elective surgeries to determine whether cTBS can cure POD in this senior patient population. ;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT03606941 -
Effect of Electroacupuncture on the Incidence of Postoperative Delirium in Elderly Patients Undergoing the Major Surgery
|
N/A | |
| Recruiting |
NCT05990790 -
The Effect of Desflurane Versus Sevoflurane Versus Propofol on Postoperative Delirium
|
Phase 4 | |
| Completed |
NCT03950440 -
Assessing the Incidence of Postoperative Delirium Following Aortic Valve Replacement
|
||
| Terminated |
NCT03337282 -
Incidence and Characteristics of Postoperative Cognitive Dysfunction in Elderly Quebec Francophone Patients
|
||
| Completed |
NCT02585128 -
Predictors of Postoperative Delirium After Transcatheter Aortic Valve Implantation
|
N/A | |
| Recruiting |
NCT02227225 -
Factors Affecting the Incidence of Postoperative Delirium in Frail Elderly
|
N/A | |
| Recruiting |
NCT01934049 -
Postoperative Recovery in Elderly Patients Undergoing Hip Hemi-arthroplasty
|
Phase 4 | |
| Terminated |
NCT00455143 -
Cognitive Protection - Dexmedetomidine and Cognitive Reserve
|
Phase 4 | |
| Recruiting |
NCT05010148 -
A Clinical Trial of Intravenous Lidocaine After Spinal Surgery to Prevent Delirium and Reduce Pain
|
Phase 3 | |
| Completed |
NCT06178835 -
EPO for Postop Delirium in Elderly Patients
|
Phase 4 | |
| Recruiting |
NCT05992506 -
Electroencephalographic Biomarker to Predict Postoperative Delirium
|
||
| Recruiting |
NCT03839784 -
Building a Platform for Precision Anesthesia in the Geriatric Surgical Patient
|
||
| Completed |
NCT04154176 -
Validation of the Greek Version of the Confusion Assessment Method Diagnostic Algorithm (CAM) and the Nursing Delirium Screening Scale (Nu-DESC) and Their Inter-rater Reliablity
|
||
| Not yet recruiting |
NCT06375265 -
Digital Sleep Optimization for Brain Health Outcomes in Older Surgical Patients
|
N/A | |
| Recruiting |
NCT05572307 -
Peripheral Blood Single Cell Sequencing Analysis of POD and CPSP in Elderly Patients After Total Knee Arthroplasty
|
||
| Active, not recruiting |
NCT03629262 -
Dexmedetomidine Supplemented Intravenous Analgesia in Elderly After Orthopedic Surgery
|
Phase 4 | |
| Not yet recruiting |
NCT05537155 -
Buccal Acupuncture for Delirium Treatment in Older Patients Recovering From Orthopedic Surgery
|
N/A | |
| Completed |
NCT01964274 -
Relevance of the Peripheral Cholinesterase-activity on Neurocognitive Dysfunctions in Surgical Patients
|
||
| Completed |
NCT01599689 -
Pilot and Feasibility Study of a Mirrors Intervention for Reducing Delirium in Older Cardiac Surgical Patients
|
N/A | |
| Active, not recruiting |
NCT03291626 -
Postoperative Delirium: EEG Markers of Sleep and Wakefulness
|