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Perioperative Immunonutrition Intervention and Oral Decontamination in Elderly Surgical Patients

Postoperative Complications Clinical Trial

Official title:
Effect of Perioperative Immunonutrition Intervention and Oral Decontamination on Postoperative Complications in Elderly: a Prospective Randomized Controlled Trial

Clinical Trial Summary

Elderly patients are vulnerable to postoperative complications. Preoperative malnutrition and poor oral hygiene are risk factors for postoperative complications especially pulmonary complications. This study aims to investigate the feasibility and efficacy of perioperative oral decontamination and immunonutrition supplement on reducing postoperative complications in elderly surgical patients.

Clinical Trial Description

This study is a prospective, single center, two-by-two factorial randomized controlled trial to evaluate the feasibility and efficacy of perioperative oral chlorhexidine decontamination and immunonutrition supplementation on postoperative complications in elderly surgical patients. Patients aged 65 years and older who are scheduled for elective non-cardiac surgeries will be recruited and randomized into four groups in 1:1:1:1 ratio (oral decontamination vs routine oral care with/without immunonutrition supplementation). ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05679661
Study type Interventional
Source Peking Union Medical College Hospital
Contact Lu Che, MD
Phone 69152020
Email tracymaobao@126.com
Status Recruiting
Phase N/A
Start date February 6, 2023
Completion date January 1, 2025
View Details
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