Postoperative Complications Clinical Trial
Official title:
Use of Melatonin for Prevention of POCD After TURP Surgery Under Spinal Anesthesia for Elderly Patients
This study aims to evaluate the possible effect of melatonin on prevention of cognitive dysfunction in the postoperative period of elderly patients undergoing transurethral resection of the prostate (TURP) under spinal anesthesia
TURP is the most common surgical procedure performed on male patients over 60 years of age to
treat benign prostatic hyperplasia.
One of the concerns, since it compromises the quality of life, is postoperative cognitive
dysfunction. It can be due to TURP Syndrome or to other causes, like changing the routine and
circadian rhythm for patients with more susceptibility.
The investigators postulate that melatonin premedication and use during the perioperative
period could avoid cognitive impairment in patients undergoing TURP surgery that didn't
develop major complications, like TURP Syndrome.
Since anesthestic technic could also influence the outcome of POCD, only patients undergoing
spinal anesthesia were included in the study,
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