Pre-operative Blood Lipid Level and Post-operative Major Adverse Cardiac Event

Postoperative Complications Clinical Trial

Official title:

The Relationship of Pre-operative Blood Lipid Level and Post-operative Major Adverse Cardiac Event Occurence

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03344224
• Other study ID #: LMACE
• Status: Completed
• Phase: N/A
• First received: November 13, 2017
• Last updated: January 3, 2018
• Start date: January 1, 2017
• Est. completion date: September 20, 2017

Study information

• Verified date: January 2018
• Source: Peking University First Hospital
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Whether the pre-operative blood lipid level and post-operative cardiovascular events is associated is unknown. This study is to find out the main blood lipid and relative protein level change and the post-operative cardiovascular events occurrence.

Description:

The participants collected data from their hospital.Patients under going non-cardiac surgery were collected. Data of Triglycerides, cholesterol, Low-density lipoprotein and High-density lipoprotein were collected perioperatively. The postoperative major cardiovascular and cerebral events were also identified and collected. Other data including perioperative information and surgeries and anesthesia data were gathered.

Logistic regression models were built and selected. Independent risk factors relative to postoperative major cardiovascular and cerebral events were screened and identified. different levels of Triglycerides, cholesterol, Low-density lipoprotein and High-density lipoprotein were analysed.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 50000
• Est. completion date: September 20, 2017
• Est. primary completion date: July 30, 2017
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years to 100 Years

Eligibility

Inclusion Criteria:

• non-cardiac surgery patients with preoperative blood lipid tests

Exclusion Criteria:

• electronic records missing or peri-operative data missing

Related Conditions & MeSH terms

• Lipid Metabolism Disorders
• Metabolic Diseases
• Postoperative Complications

Intervention

Diagnostic Test:
• laboratory test
laboratory test

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Peking University First Hospital

References & Publications (1)

Leardi S, Altilia F, Delmonaco S, Cianca G, Pietroletti R, Simi M. [Blood levels of cholesterol and postoperative septic complications]. Ann Ital Chir. 2000 Mar-Apr;71(2):233-7. Italian. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	cardiovascular events	such as acute myocardial infarction	30 days postoperatively