Predictive Model for Postoperative Mortality

Postoperative Complications Clinical Trial

Official title:

Predictive Model for Postoperative Mortality in Adult Emergency Surgical Patients Under General Anesthesia

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT02947789
• Other study ID #: HE581131
• Status: Completed
• Phase: N/A
• First received: October 26, 2016
• Last updated: May 10, 2017
• Start date: September 2016
• Est. completion date: February 2017

Study information

• Verified date: May 2017
• Source: Khon Kaen University
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Surgery has risk of morbidity and mortality. Risk factors include: patient factors; surgical factors; and anesthetic factors. The risk is much higher in emergency cases. The study of relevant risk factors can lead to improvement in patient management and reduction in mortality.

Description:

Objective: To identify risk factors for postoperative mortality within 3 days in adult patients undergoing emergency surgery and construct a predictive model.

Methods: This will be a retrospective, exploratory and analytical study. All medical records of adult patients undergoing emergency surgery between January 2013 to December 2014 will be used to analyze for relevant risk factors using binary logistic regression analysis. A predictive model to predict postoperative morbidity within 3 days will be constructed.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 740
• Est. completion date: February 2017
• Est. primary completion date: February 2017
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Emergency surgery

• Age => 18 years

Exclusion Criteria:

• Caesarean section

• Incomplete medical record

Related Conditions & MeSH terms

• Postoperative Complications

Intervention

Procedure:
• Emergency surgery
Patients undergoing emergency surgery

Locations

Country	Name	City	State
Thailand	Faculty of Medicine, Khon Kaen University	Khon Kaen

Sponsors (1)

Lead Sponsor	Collaborator
Khon Kaen University

Country where clinical trial is conducted

Thailand, 

References & Publications (5)

Akinbami F, Askari R, Steinberg J, Panizales M, Rogers SO Jr. Factors affecting morbidity in emergency general surgery. Am J Surg. 2011 Apr;201(4):456-62. doi: 10.1016/j.amjsurg.2010.11.007. — View Citation

Fukuda N, Wada J, Niki M, Sugiyama Y, Mushiake H. Factors predicting mortality in emergency abdominal surgery in the elderly. World J Emerg Surg. 2012 May 11;7(1):12. doi: 10.1186/1749-7922-7-12. — View Citation

Ingraham AM, Cohen ME, Bilimoria KY, Raval MV, Ko CY, Nathens AB, Hall BL. Comparison of 30-day outcomes after emergency general surgery procedures: potential for targeted improvement. Surgery. 2010 Aug;148(2):217-38. doi: 10.1016/j.surg.2010.05.009. — View Citation

Matsuyama T, Iranami H, Fujii K, Inoue M, Nakagawa R, Kawashima K. Risk factors for postoperative mortality and morbidities in emergency surgeries. J Anesth. 2013 Dec;27(6):838-43. doi: 10.1007/s00540-013-1639-z. Epub 2013 May 23. — View Citation

Wilson I, Paul Barrett M, Sinha A, Chan S. Predictors of in-hospital mortality amongst octogenarians undergoing emergency general surgery: a retrospective cohort study. Int J Surg. 2014 Nov;12(11):1157-61. doi: 10.1016/j.ijsu.2014.08.404. Epub 2014 Sep 16 — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Postoperative mortality within 3 days	Patient die postoperatively within 3 day3	through study completion, an average of 1 week