Old Blood and Postoperative Complications

Postoperative Complications Clinical Trial

Official title:

The Effects of Old Red Blood Cell Transfusion on Morbidity in Patients Undergoing Revision Total Hip Arthroplasty: Retrospective Study

Clinical Trial Details — Status: Withdrawn

Administrative data

• NCT number: NCT02575820
• Other study ID #: B-1510/318-112
• Status: Withdrawn
• Phase: N/A
• First received: October 11, 2015
• Last updated: May 12, 2016
• Start date: November 2015
• Est. completion date: May 2016

Study information

• Verified date: May 2016
• Source: Seoul National University Hospital
• Contact: n/a
• Is FDA regulated: No
• Health authority: Institutional Review Board: Korea
• Study type: Observational

Clinical Trial Summary

The investigators sought to examine the effects of 'old' red blood cells on mortality and morbidity of patients who undergoing revision hip replacement arthroplasty. The investigators hypothesis is that patients have an increased risk of mortality and infection after 'old' red blood cells transfusions compared with those who received 'new' transfusions.

Recruitment information / eligibility

• Status: Withdrawn
• Enrollment: 0
• Est. completion date: May 2016
• Est. primary completion date: May 2016
• Accepts healthy volunteers: No
• Gender: Both
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Patients who underwent revision total hip replacement

Exclusion Criteria:

• Patients who were not given red blood cells

• Patients who were given two units of which one unit was old and one was new

Study Design

Observational Model: Cohort, Time Perspective: Retrospective

Related Conditions & MeSH terms

• Orthopedics
• Postoperative Complications
• Red Blood Cells

Intervention

Procedure:
• Old red blood cells transfusion
Red blood cells (shelf life > 14 days) transfusion during the operation (total hip replacement arthroplasty)
• New red blood cells transfusion
Red blood cells (shelf life =< 14 days) transfusion during the operation (total hip replacement arthroplasty)

Locations

Country	Name	City	State
Korea, Republic of	Seoul National University Bundang Hospital	Seongnamsi

Sponsors (1)

Lead Sponsor	Collaborator
Seoul National University Hospital

Country where clinical trial is conducted

Korea, Republic of, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Mortality		postoperative 7 days	No
Primary	Sepsis		postoperative 7 days	No
Primary	Wound infection		postoperative 7 days	No
Primary	Postoperative delirium		postoperative 7 days	No
Primary	Postoperative bleeding		postoperative 7 days	No
Secondary	Transfusion related lung injury		postoperative 7 days	No
Secondary	Pulmonary edema		postoperative 7 days	No
Secondary	Pulmonary effusion		postoperative 7 days	No
Secondary	Myocardial ischemia		postoperative 7 days	No
Secondary	Pulmonary thromboembolism		postoperative 7 days	No
Secondary	Renal failure		postoperative 7 days	No
Secondary	Hepatic failure		postoperative 7 days	No