Postoperative Complications Clinical Trial
The hypothesis of this study is that the "Open lung approach" ( recruitment and PEEP) during
general anaesthesia reduces atelectasis formation and improves respiratory function in the
immediate post-operative period after major abdominal surgery.
This is a prospective, randomized, controlled clinical-trial,performed in patients
undergoing major abdominal surgery, to compare the effects on the post-operative pulmonary
complications of two different intraoperative ventilatory strategies during general
anaesthesia: 1- Control Group: PEEP 0 cmH2O without recruitment manoeuvre; 2- Treatment
Group:recruitment manoeuvre (after intubation and before extubation) and PEEP 10 cmH2O In
the post-operative period the following variables will be recorded at the first, third and
fifth postoperative day: 1- Gas-exchange in air; 2- Chest X-ray for atelectasis evaluation;
3- signs of pulmonary complication (cough, secretions, dyspnea, thoracic pain)
n/a
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment
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