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Postoperative Complications clinical trials

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NCT ID: NCT02666300 Recruiting - Clinical trials for Postoperative Complications

To Compare the Incidence of POST Between a TaperGuard ETT and Cylindrical-shaped ETT Under High Cuff Pressure

Start date: December 2015
Phase: N/A
Study type: Interventional

Postoperative Sore Throat (POST) is supposed to be the most frequently occurred respiratory complication related to endotracheal intubation .Whether the new type of ETT(TaperGuard ETT) to decrease or to increase the complications of general anesthesia compared with Cylindrical-shaped ETT is still unknown .In this study ,we will compare the different incidence of complications following general anesthesia between TaperGuard ETT and Cylindrical-shaped ETT under high endotracheal tube cuff pressure.

NCT ID: NCT02662257 Completed - Delirium Clinical Trials

Impact of Anesthesia Maintenance Methods on Incidence of Postoperative Delirium

Start date: April 1, 2015
Phase: N/A
Study type: Interventional

Surgery is one of the major treatment methods for patients with malignant tumor. And, alone with ageing process, more and more elderly patients undergo surgery for malignant tumor. Evidence emerges that choice of anesthetics, i.e., either inhalational or intravenous anesthetics, may influence the outcome of elderly patients undergoing cancer surgery. Delirium is a commonly occurred early postoperative cognitive complication in the elderly, and its occurrence is associated with the worsening outcomes. Choice anesthetics may influence the occurrence of postoperative delirium. However, evidence in this aspect is conflicting.

NCT ID: NCT02659553 Completed - Clinical trials for Post-operative Complications

Impact of Graft Steatosis on Post-operative Complications After Liver Transplantation

Start date: January 2015
Phase: N/A
Study type: Observational

1. Clinical impact of graft steatosis on postoperative complications after OLT. 2. Recommendations to improve outcomes after transplantation of steatotic livers and increase donor pool.

NCT ID: NCT02658318 Completed - Cleft Palate Clinical Trials

Postoperative Complications After Cleft Palate Closure in Patients With Pierre Robin Sequence: Operative Considerations

Start date: January 2011
Phase: N/A
Study type: Observational

In cleft surgery there is no current general agreement on the treatment strategy of patients with the Pierre Robin Sequence. The timing of surgery and the surgical approach depends on the treating physician or the hospital facility. Literature regarding peri- and postoperative complications in the target population are lacking. The investigators aim to retrospectively review the charts of all cleft patients, both PRS and non-PRS, treated with an adapted Furlow palatoplasty between 01/01/2011 and 31/08/2015. The incidence of peri- and postoperative complications, with a specific focus on respiratory complications, will be examined. The value of demographic, surgical and postoperative parameters will be examined as potential risk factors for the development of complications.

NCT ID: NCT02658006 Completed - Acute Kidney Injury Clinical Trials

Evaluation of Monitoring TECHNOlogies in the PERI-OPerative Care of Cardiac Surgical Patients

TechnoPeriOp
Start date: November 2015
Phase: N/A
Study type: Observational

The purpose of this prospective observational cohort study is to evaluate multimodal monitoring technologies in the perioperative care of cardiac surgical patients. Right ventricular pressure tracings, near infrared spectroscopy (NIRS) and transthoracic ultrasonography will be studied for their ability to detect and predict complications such as right ventricular failure, renal failure and respiratory failure.

NCT ID: NCT02647476 Completed - Gastric Cancer Clinical Trials

Postoperative Enteral Immunonutrition in Gastric Cancer

Start date: November 2004
Phase: Phase 3
Study type: Interventional

Immunomodulating enteral nutrition in the perioperative period may reduce postoperative complications in cancer patients. Little is known if this effect translates to the better survival. The aim of study was to assess the impact of postoperative immunomodulating enteral nutrition on postoperative complications and survival of gastric cancer patients. The group of 98 gastric cancer patients were randomly assigned for postoperative immunomodulating enteral nutrition n=44 (Reconvan ,Fresenius Kabi), or standard enteral nutrition n=54 (Peptisorb, Nutricia). Postoperative complications, mortality, 6-month, 1-year and 5-year survival were analyzed.

NCT ID: NCT02644876 Completed - Clinical trials for Postoperative Complications

Preventive Effects of Penehyclidine Hydrochloride Inhalation on Postoperative Pulmonary Complications

Start date: September 1, 2015
Phase: Phase 4
Study type: Interventional

Postoperative pulmonary complications (PPCs) are major causes of postoperative morbidity, mortality, and prolonged hospital stay.The incidence of PPCs may be as high as 41% to 75% in high-risk patients. Bronchodilator is frequently used in high-risk patients to prevent PPCs. Penehyclidine is a new anticholinergic agent which selectively block M1 and M3, but not M2 receptors. A pilot study of the investigators showed that prophylactic penehyclidine inhalation reduced the incidence of bronchospasm and the use of aminophylline in elderly patients after long-duration surgery. The purpose of this study is to investigate whether prophylactically penehyclidine inhalation could decrease the incidence of PPCs in high-risk patients after major intrathoracic and upper intraabdominal surgery.

NCT ID: NCT02641223 Completed - Clinical trials for Post-laminectomy Syndrome

Evaluation of Objective Outcomes With the Use of an Activity Tracker During the Trial Period of Spinal Cord Stimulation

Start date: November 2015
Phase: N/A
Study type: Observational

For this study the investigators will conduct five-day trial periods for spinal cord stimulator (SCS) effectiveness—once a patient is deemed to be a possible SCS candidate, the trial leads are implanted and they are asked to return to clinic in five days to evaluate the effectiveness of the trial. The primary outcome for this study will be a comparison of daily energy expenditure (EE), in units of kcal/day, prior to and after the trial implantation of the SCS leads and external pulse generator. Patients will wear the accelerometer device twenty-four hours a day for five days prior to the trial lead implantation to obtain baseline values, have the trial leads implanted in the procedure clinic, then continue to wear the accelerometer for another five days. Baseline and post-SCS energy expenditure values will be compared. The secondary outcomes for this study will be steps taken, hours of sleep, and Oswestry Disability Index (ODI, as described in appendix 1) during the pre and post trial implantation periods. SCS itself is not a research procedure in this study, rather it is part of routine medical care for patients who would benefit from the procedure.

NCT ID: NCT02635542 Completed - Clinical trials for Postoperative Complications

Effect of Neuromuscular Blockade on Pulmonary Complications in Elective Cardiac Surgery

Start date: March 2016
Phase: Phase 4
Study type: Interventional

The investigators will conduct a prospective, randomized trial to assess the impact of neuromuscular blockade on early (<72 hours post-ICU admission) postoperative respiratory complications in cardiac surgical patients. The study will compare continual neuromuscular blockade with cisatracurium to a single dose of succinylcholine during general anesthesia for cardiac surgery.

NCT ID: NCT02631304 Completed - Clinical trials for Postoperative Complications

Delirium in Elderly Undergoing Cardiac Surgery and the Significance of CholinEsterase Activity

DECCEP
Start date: July 2015
Phase:
Study type: Observational

The purpose of this study is to assess the association between the "point-of-care" (POC) measured ChE activity (Acetylcholinesterase (ChE) + Buturylcholinesterase (ChE)) and postoperative delirium in elderly patients undergoing cardiac surgery. Furthermore the investigators aim to identify factors, which influence the baseline levels and the time course of ChE activity.