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Clinical Trial Summary

In patients undergoing cardiac surgery, perioperative anemia is an important factor in surgical recovery. In addition to the low preoperative hemoglobin level, the delayed recovery of the postoperative hemoglobin level is an important problem affecting the incidence of postoperative anemia. Erythroferron is the early response to of the red blood cell production in stressful situations such as anemia, bleeding, and hypoxia. Therefore, it is thought that acute blood loss and systemic inflammatory reaction that inevitably occurs after cardiac surgery will synthesize erythroferron, which helps to restore hemoglobin level at postoperative period by promoting hematopoiesis by simultaneously inhibiting hepcidin and activating hematopoiesis. In this study, the investigators will investigate the association between Erythroferron and perioperative hemoglobin levels in patient undergoing heart valve surgery.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT05384054
Study type Observational
Source Yonsei University
Contact Young Lan Kwak
Phone +82-2-2228-8500
Email ylkwak@yuhs.ac
Status Not yet recruiting
Phase
Start date May 2022
Completion date March 2024

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Completed NCT01913808 - Comparing Intravenous and Oral Iron in Postoperative Anemia Phase 4
Completed NCT02519088 - A New Approach to a Personalized Patient Blood Management Program (pPBM) in Total Hip Arthroplasty (THA) N/A