The Effect of Different Local Anesthetic Volumes on Postoperative Analgesia for Thoracotomy Patients With Erector Spinae Plane Block

Postoperative Analgesia Clinical Trial

Official title:

The Effect of Different Local Anesthetic Volumes for Thoracotomy Patients With Erector Spinae Plane Block

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT05083845
• Other study ID #: E.Kurul-E1-21-1964
• Status: Completed
• Phase: N/A
• Start date: August 25, 2021
• Est. completion date: July 9, 2022

Study information

• Verified date: July 2022
• Source: Atatürk Chest Diseases and Chest Surgery Training and Research Hospital
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

It is widely accepted that thoracotomy causes severe acute pain. This increases the frequency of postoperative pulmonary complications and postoperative morbidity. Many analgesic methods have been proposed for thoracotomy pain, including thoracic epidural analgesia (TEA), thoracic paravertebral block (TPVB), intercostal nerve blocks (ICSB), erector spinae plane block (ESPB), serratus anterior plane block (SAPB). Among these methods, ultrasound-guided TPVB and ESPB are the most used methods. TPVB has left its place to newer techniques such as ESPB due to its proximity to the pleura and its deeper location. ESPB is more superficial, easy to access, and less likely to have complications. In addition, ESPB application is increasing in patients who underwent thoracotomy and VATS. There is no consensus on the dose of analgesia in these studies. There are studies on volumes between 10 ml and 40 ml in the literature. In this study, it was aimed to compare the volumes of 20 ml and 30 ml containing local anesthetic at the same concentration (0.25% bupivacaine) of ESPB block to be performed with USG in patients who underwent thoracotomy.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 60
• Est. completion date: July 9, 2022
• Est. primary completion date: June 9, 2022
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years to 65 Years

Eligibility

Inclusion Criteria:

• 18 to 65 years old

• ASA physical status I-II-III

• BMI 18 to 30 kg/m2

• Elective thoracotomy surgery

Exclusion Criteria:

• Patient refusing the procedure

• Emergency surgery

• History of chronic opioid or analgesic used

Related Conditions & MeSH terms

• Erector Spinae Plane Block
• Local Anesthetic
• Postoperative Analgesia
• Thoracotomy

Intervention

Procedure:
• Same blocks with different local anesthetic volume
Erector spinae plane block with different local anesthetic volumes will be applied to the patients under real-time ultrasound guidance.

Locations

Country	Name	City	State
Turkey	Ankara Atatürk Chest Disease and Chest Surgery Training and Research Hospital	Kecioren	Ankara

Sponsors (1)

Lead Sponsor	Collaborator
Atatürk Chest Diseases and Chest Surgery Training and Research Hospital

Country where clinical trial is conducted

Turkey, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Pain Scores	Pain will be assessed at rest and while coughing using the visual analog scale on a scale from 0 (no pain) to 10 (worst pain). Pain assessment will be done at 1st, 2nd, 4th, 8th, 16th, 24th and 48th hours after surgery.	48 hours after surgery
Secondary	Morphine Consumption	Morphine consumption for 24 hours will be recorded	24 hours after surgery