Postherpetic Neuralgia Clinical Trial
Official title:
Association Between Some Candidate Single Nucleotide Polymorphisms and Postherpetic Neuralgia
| NCT number | NCT03708653 |
| Other study ID # | 2018-0904 |
| Secondary ID | |
| Status | Completed |
| Phase | |
| First received | |
| Last updated | |
| Start date | April 1, 2018 |
| Est. completion date | February 13, 2019 |
| Verified date | September 2018 |
| Source | Second Affiliated Hospital, School of Medicine, Zhejiang University |
| Contact | n/a |
| Is FDA regulated | No |
| Health authority | |
| Study type | Observational |
Postherpetic neuralgia (PHN) is a common condition and affecting 5 to 30% of the herpes zoster patients. In some cases, the pain remained refractory after first and second line treatment for herpes zoster. This suggests that there may be genetic variants that make some patients susceptible to PHN. Using saliva samples from herpes zoster patients the investigators are going to analyze the relationship between single nucleotide polymorphisms (SNPs) in genes that are known to be involved in pain and PHN.
| Status | Completed |
| Enrollment | 181 |
| Est. completion date | February 13, 2019 |
| Est. primary completion date | February 13, 2019 |
| Accepts healthy volunteers | No |
| Gender | All |
| Age group | 50 Years and older |
| Eligibility |
Inclusion Criteria: - Age more than 50 years - Clinically defined herpes zoster patients Exclusion Criteria: - Patients not able to provide informed consent |
| Country | Name | City | State |
|---|---|---|---|
| China | The second affiliated hospital of Zhejiang University | Hangzhou | Zhejiang |
| Lead Sponsor | Collaborator |
|---|---|
| Second Affiliated Hospital, School of Medicine, Zhejiang University |
China,
| Type | Measure | Description | Time frame | Safety issue |
|---|---|---|---|---|
| Primary | correlation between pain SNPs and PHN | At Enrollment |
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