Clinical Trials Logo

Clinical Trial Details — Status: Completed

Administrative data

NCT number NCT04041089
Other study ID # 18-AOI-02
Secondary ID
Status Completed
Phase N/A
First received
Last updated
Start date September 2, 2019
Est. completion date June 15, 2022

Study information

Verified date February 2023
Source Centre Hospitalier Universitaire de Nice
Contact n/a
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

Posterior cortical atrophy (PCA) is manifested by neuro-visual disorders that alter the spatial location of objects, their manipulation and/or recognition. Its etiology is most often neurodegenerative, with a major impact on the autonomy and mood of patients and their families. Few studies have focused on non-medication management of these disorders. The present study thus has a double objective: the development of a complete tool to work on the recognition, localization and/or manipulation of objects; and the evaluation of the effectiveness of this type of management.


Recruitment information / eligibility

Status Completed
Enrollment 3
Est. completion date June 15, 2022
Est. primary completion date June 15, 2021
Accepts healthy volunteers No
Gender All
Age group 50 Years and older
Eligibility Inclusion Criteria: - Age >50 years old - Male or Female - Patients with a diagnosis of PCA according to the criteria of Tang-Wai et al (2004) - MMS>15 - Voluntary, written and informed consent of the patient himself or its legal representative (guardian/curator), with oral consent of the patient in all cases - Anti-Alzheimer's and psychotropic treatments stable for one month, if taken by the patient - Affiliation to a social security system Exclusion Criteria: - Uncorrected visual disorders with non-degenerative etiology (AV<0.5) - Person under the protection of justice - Pregnant women (a pregnancy test will be performed in premenopausal women)

Study Design


Related Conditions & MeSH terms


Intervention

Behavioral:
Recognition of objects
Name of shapes / colors / images / objects Classification of shapes / colors / images / objects
Location of objects
Search for frequent/rarse targets among distractors sharing one or more characteristics with the target Hit/catch a stationary/mobile target as quickly as possible
Manipulation of objects
Storage of shapes/objects Use of everyday objects (pen, cutlery, etc.)

Locations

Country Name City State
France Institut Claude Pompidou - Centre Mémoire de Ressources et de Recherche du CHU de Nice Nice Alpes-Maritime

Sponsors (1)

Lead Sponsor Collaborator
Centre Hospitalier Universitaire de Nice

Country where clinical trial is conducted

France, 

Outcome

Type Measure Description Time frame Safety issue
Primary Effectiveness evaluation Effectiveness will be evaluated a score based on success rate (from 0 to 10), reaction time and eye-recording . At week 34
See also
  Status Clinical Trial Phase
Completed NCT01095744 - Influence of Age on Amyloid Load in Alzheimer's Disease and in Atypical Focal Cortical Alzheimer's Disease N/A
Recruiting NCT03153371 - Early-onset Alzheimer's Disease Phenotypes: Neuropsychology and Neural Networks
Not yet recruiting NCT04150198 - MECHANISMS OF NEURONAL RESILIENCE IN ALZHEIMER'S DISEASE AND ITS FOCAL VARIANTS: A PET/MR STUDY N/A