Clinical Trials Logo
  1. Home
  2. Posterior Capsule Opacification
  3. NCT01125345

Posterior Capsule Opacification (PCO) With Single Piece Hydrophobic Versus Hydrophillic Intraocular Lens (IOL)

Posterior Capsule Opacification Clinical Trial

Official title:
A Prospective Controlled Clinical Trial to Evaluate the Posterior Capsule Opacification in Contralateral Eyes Implanted With Single Piece Hydrophobic AcrySof IOL and Single Piece Hydrophilic Acrylic IOLs

Clinical Trial Summary

The purpose of the study was to compare the postoperative PCO results of the single-piece hydrophobic Acrylic IOLs versus the newer generation single-piece hydrophilic Acrylic IOLs in patients undergoing bilateral cataract surgery.

Clinical Trial Description

Amongst several surgical techniques and IOL technology that influence the opacification of the posterior capsule, the role of IOL material and optic design remain crucial in determining its development. The single-piece Acrylic IOLs with a hydrophobic surface have been widely used in practice. The single-piece Acrylic IOLs with a hydrophilic surface became commercially available more recently. Although there is a study that compared the single piece hydrophobic and the single piece hydrophilic IOL, it was conducted on the older generation of the hydrophilic IOL. Moreover, experimental and clinical study has been performed to evaluate the posterior capsule opacification between the Hydrophilic acrylic IOL with a sharp optic edge design excluding the optic-haptic junction, versus the newer generation hydrophilic IOL design which has an improved 360-degree sharp edge, with results favouring the latter design. There is little data that compares the single-piece Acrylic IOLs with a hydrophobic surface to the newer generation single-piece Acrylic IOLs with a hydrophilic surface. Because the IOL characteristics play a crucial role to prevent posterior capsule opacification (PCO), it is of clinical importance, as well as investigational interest to assess the PCO following implantation of these IOLs. We conducted a prospective, randomised, intra-individual study to compare the 3 year postoperative PCO results of the single-piece hydrophobic Acrylic IOLs versus the newer generation single-piece hydrophilic Acrylic IOLs in patients undergoing bilateral cataract surgery. ;

Study Design

Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Outcomes Assessor), Primary Purpose: Prevention

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01125345
Study type Interventional
Source Iladevi Cataract and IOL Research Center
Contact
Status Completed
Phase Phase 4
Start date January 2006
Completion date December 2009
View Details
See also
  Status Clinical Trial Phase
Recruiting NCT06060041 - IC-8 Apthera IOL New Enrollment Post Approval Study
Completed NCT03321253 - Changes of Macular Pigment and Parameters of Eyes After YAG Laser Treatment in Cases With Capsule Opacification N/A
Recruiting NCT03701139 - Posterior Capsulotomy in Cataract Complicated With Primary Posterior Capsule Opacification. N/A
Recruiting NCT05501535 - Refraction Changes After Using ND: YAG LASER In Treatment of Posterior Capsular Opacification In Pseudo Phakic Eye
Completed NCT03184428 - Posterior Capsule Opacification Following Cataract Surgery With Implantation of the MICS IOL L313
Recruiting NCT02445274 - Two Different Cataract Surgical Procedures to Prevent Posterior Capsule Opacification N/A
Completed NCT02968290 - Quantification of Posterior Capsule Opacification in Pediatric Cataract N/A
Completed NCT01936701 - Comparison of the Effect of Hydrophobic Acrylic and Silicone 3-piece IOLs on Posterior Capsule Opacification N/A
Completed NCT01786356 - Posterior Capsule Opacification and Frequency of Nd:YAG Treatment and of Two IOLs: Hoya iMics Y-60H vs. Bausch&Lomb MI60 (MIMI) N/A
Completed NCT03192826 - Brinzolamide/Brimonidine Combination vs Brimonidine 0.2% in the Prevention of IOP Rise After Nd-YAG Laser Capsulotomy Phase 4
Completed NCT00855491 - Posterior Capsule Opacification (PCO) With AcrySof Single-Piece IOL N/A
Completed NCT03831074 - Posterior Capsule Opacification and Optical Quality of Different Hydrophobic Acrylic Intraocular Lenses N/A
Completed NCT01734343 - Posterior Capsule Opacification Development With Two Different Intraocular Lenses N/A
Recruiting NCT03857685 - LEC Proliferation in Vivo and In-vitro
Active, not recruiting NCT03605160 - An Innovative Method Fluid-jet to to Remove Residual Lens Fibers N/A
Completed NCT04007965 - Novel Technique of Pneumatic Posterior Capsulorhexis for Treatment and Prevention of Posterior Capsular Opacification N/A
Recruiting NCT03857412 - Posterior Capsule Opacification After Lens Capsule Polishing N/A
Completed NCT02975895 - Outcome of Different IOLs in Patients With and Without Uveitis N/A
Completed NCT02491918 - Clinical Trial : Complications of in the Bag IOL Versus Optic Capture of IOL in Pediatric Cataract Surgery N/A
Recruiting NCT06083025 - Influence of CleaRing Open-capsule Device on Refractive Predictability in Cataract Patients (Part 2) N/A