Topical IL-1-Ra for Treatment of Posterior Blepharitis

See also
Status	Clinical Trial	Phase
Completed	`NCT02952079` - Comparison of BlephEx to MiBoflo as Treatment Options for Blepharitis	N/A
Completed	`NCT04469998` - Evaluation of AXR-270 for the Treatment of Posterior Blepharitis Associated With Meibomian Gland Dysfunction	Phase 2
Completed	`NCT01783860` - Oral Azithromycin Versus Doxycycline in Posterior Blepharitis	Phase 2
Active, not recruiting	`NCT01456780` - Efficacy of Zylet vs. Lotemax for the Treatment of Ocular Surface Inflammation/MGD/Blepharitis	Phase 4

See also

Status

Clinical Trial

Phase

Completed

NCT02952079 - Comparison of BlephEx to MiBoflo as Treatment Options for Blepharitis

N/A

Completed

NCT04469998 - Evaluation of AXR-270 for the Treatment of Posterior Blepharitis Associated With Meibomian Gland Dysfunction

Phase 2

Completed

NCT01783860 - Oral Azithromycin Versus Doxycycline in Posterior Blepharitis

Phase 2

Active, not recruiting

NCT01456780 - Efficacy of Zylet vs. Lotemax for the Treatment of Ocular Surface Inflammation/MGD/Blepharitis

Phase 4

Interventional studies are often prospective and are specifically tailored to evaluate direct impacts of treatment or preventive measures on disease.

Observational studies are often retrospective and are used to assess potential causation in exposure-outcome relationships and therefore influence preventive methods.

Expanded access is a means by which manufacturers make investigational new drugs available, under certain circumstances, to treat a patient(s) with a serious disease or condition who cannot participate in a controlled clinical trial.

Clinical trials are conducted in a series of steps, called phases - each phase is designed to answer a separate research question.

Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.

NCT number	NCT00681109
Study type	Interventional
Source	Massachusetts Eye and Ear Infirmary
Contact
Status	Completed
Phase	Phase 1/Phase 2
Start date	January 2008
Completion date	October 2010

Topical IL-1-Ra for Treatment of Posterior Blepharitis

Clinical Trial Summary

Clinical Trial Description

Study Design

Related Conditions & MeSH terms