A Postoperative Sore Throat After Lumbar Spine Surgery in the Prone Position

Post Operative Sore Throat Clinical Trial

Official title:

The Effect of Dexmedetomidine and Remifentanil Infusion on Postoperative Sore Throat After Lumbar Spine Surgery in the Prone Position

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT05345574
• Other study ID #: YUMC 2018-09-029
• Status: Recruiting
• Phase: N/A
• Start date: December 26, 2018
• Est. completion date: December 31, 2022

Study information

• Verified date: April 2022
• Source: Yeungnam University College of Medicine
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

This study was performed to compare the effect of dexmedetomidine and remifentanil on the incidence and severity of postoperative sore throat in patients undergoing spinal surgery in the prone position who are at risk of developing postoperative sore throat.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 104
• Est. completion date: December 31, 2022
• Est. primary completion date: December 1, 2022
• Accepts healthy volunteers: No
• Gender: All
• Age group: 20 Years to 65 Years

Eligibility

Inclusion Criteria:

1. American Society of Anesthesiologists (ASA) physical status classification I and II

2. Undergoing lumbar spine surgery in prone position

Exclusion Criteria:

1. Pre-existing sore throat, hoarseness, or upper respiratory tract infection

2. Allergy to the study drugs

3. Anticipated difficult airways

4. More than two attempts at intubation

Related Conditions & MeSH terms

• Pharyngitis
• Post Operative Sore Throat

Intervention

Drug:
• dexmedetomidine infusion
dexmedetomidine as anaesthetic adjuvant
• remifentanil infusion
remifentanil as anaesthetic adjuvant

Locations

Country	Name	City	State
Korea, Republic of	Eun kyung Choi	Daegu	Korea (the Republic Of)

Sponsors (1)

Lead Sponsor	Collaborator
Yeungnam University College of Medicine

Country where clinical trial is conducted

Korea, Republic of, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	incidence of postoperative sore throat at rest	0=none; 1=occur	1 hour after surgery
Primary	incidence of postoperative sore throat at swallowing	0=none; 1=occur	1 hour after surgery
Primary	severity of postoperative sore throat at rest	4-point scale (0=none; 1=mild; 2=moderate; 3=severe)	1 hour after surgery
Primary	severity of postoperative sore throat at swallowing	4-point scale (0=none; 1=mild; 2=moderate; 3=severe)	1 hour after surgery