Post Date Clinical Trial
Official title:
Variability in Middle Cerebral Artery Doppler Measurements in Uncomplicated Term Pregnancies.
Doppler measurements in the Middle Cerebral Artery (MCA) is a part of the assessment for
assessing fetal well-being in complicated pregnancy, including Intra Uterine Growth
Retardation and Fetal Anemia.
The use of this Doppler measurement in uncomplicated term pregnancies is not a common
practice due to lack of information. However, several studies use the MCA Pulsatility Index
(PI) as part of the Cerebro-Placental-Ratio (CPR) measurment at term.
The purpose of this trial is to assess MCA Doppler variability in term, uncomplicated
pregnancy.
Measuring the resistance in the fetal middle cerebral artery (MCA) is an important factor in
assessing fetal well-being. On its own, the Pulsatility Index (PI) in the MCA may indicate a
decrease in fetal oxygenation. Furthermore, the PI measured in the Fetal MCA is an index
parameter in the calculation of the Cerebro-Placental Ratio (CPR) used to evaluate whether
there is an existing disturbance in the Placental-Umbilical and Feto-cerebral circulations.
The CPR is a measurement that enables practitioners to predict the fetuses reaction to
intrauterine hypoxemia. The CPR measurement is commonly used to evaluate small for
gestational age (SGA) fetuses and to distinguish between constitutionally small fetuses and
ones that suffer from placental insufficiency. For those who suffer from placental
insufficiency, the CPR measurement is an aid in deciding the optimal time and mode of
delivery.
Recently, researchers pondered if the CPR measurement may aid in predicting disturbance in
fetal oxygenation during delivery. A number of studies have showed that appropriate for
gestational age fetuses with abnormal CPR measurements may be susceptible to delivery
complications in the same manner as fetuses who suffer from placental insufficiency. The
question that is yet to be answered is whether the MCA measurement reliable in term
pregnancies. This question arises due to the impression that the MCA measurement at term is
highly variable, even when taken under optimal conditions.
The aim of this study is to evaluate the intra-observer variability in the MCA measurement
under optimal conditions, in Uncomplicated Term Pregnancies.
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Observational Model: Cohort, Time Perspective: Prospective
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Not yet recruiting |
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|
N/A |