KTP Laser vs Pulsed Dye Laser for Port-Wine Stains

Port-Wine Stain Clinical Trial

Official title: Potassium Tetanyl Phosphate Laser vs Pulsed Dye Laser for Treating Port-Wine Stains - A Prospective, Split-Side Study

Status Recruiting

Clinical Trial Summary

To compare the efficacy and safety of 532nm KTP laser and 585 nm pulsed dye laser for treating port-wine stains.

Clinical Trial Description

Nevus flammeus is a vascular, primarily capillary malformation visible from birth on. In rare cases, it may also affect venous and/or arterial vascular systems of the skin or other organs [1]. It occurs in 0.3%-0.5% of the population [1], i.e. in about 3-4 out of 1000 newborns, and is thus the most frequent vascular malformation in children. The cause is a permanent dilatation of the capillary vessels, which is caused by a lack of sympathetic nerve fibers or a lower density of the same.

First-line therapy of port-wine stains consists of laser treatment with the long-pulsed dye laser [2] with a wavelength of 595nm. Treatment must be performed at least 10 times at intervals of about 8 weeks and leads to lightening and reduction of lesions. In recent years, problems have often arisen in care of port-wine stain patients because dye lasers often failed due to the instability of technology, resulting in treatment delays. Novel long-pulsed KTP lasers may be a sufficient alternative to pulsed dye lasers in treatment of port-wine stains. ;

Related Conditions & MeSH terms

• Hemangioma, Capillary
• Port-Wine Stain

• NCT number: NCT05771311
• Study type: Interventional
• Source: Universitätsklinikum Hamburg-Eppendorf
• Contact: L Nguyen, MD
• Phone: +49 (0)40 7410-0
• Email: l.nguyen@uke.de
• Status: Recruiting
• Phase: N/A
• Start date: February 1, 2023
• Completion date: August 1, 2023