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Pilot Study on the Use of the Matrix Radiofrequencyfor Treatment of Port Wine Stain Birthmarks

Port Wine Stain Clinical Trial

Official title:
Pilot Study on the Use of the Matrix Radiofrequency for Treatment of Port Wine Stain Birthmarks

Clinical Trial Summary

Port wine stain, also called nevus flammeus, is a congenital, cutaneous vascular malformation involving post-capillary venules which produces a light pink to red to dark-red-violet discoloration of the skin. It is estimated that Port wine stain occurs in 3 children per 1,000 live births. Approximately 900,000 individuals in the United States and twenty million people worldwide have Port wine stain birthmarks .

Clinical Trial Description

The purpose of this research study is to improve port wine stain treatment after Matrix Radiofrequency device treatment. The Matrix Radiofrequency device energy generates fractional deep dermal heating in the region of the electrode matrix to induce skin injury, thus eliciting a wound healing response. Less affected tissue surrounding the matrix points may be stimulated by heat which helps accelerate the healing process, while at the same time minimizing adverse effects such as scarring or changes in the normal skin pigmentation. The researcher can determine Port wine stain areas treated with the Matrix Radiofrequency device will have improved Port wine stain blanching responses as compared to those areas treated by pulsed dye laser. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01166919
Study type Interventional
Source University of California, Irvine
Contact
Status Withdrawn
Phase Phase 1
Start date December 2009
Completion date October 2011
View Details
See also
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Completed NCT03948997 - The Role of Angiogenesis-related Pathways in the Development of Port Wine Stains N/A
Completed NCT01364857 - French National Cohort of Children With Port Wine Stain N/A
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Completed NCT00800722 - A Randomized Trial to Study Combined Pulsed Dye Laser and Rapamycin Treatment of Port Wine Stain Birthmarks. Phase 1
Completed NCT00585247 - Combining Topical Imiquimod 5% Cream With a Pulsed Dye Laser to Treat Port Wine Stain Birthmarks N/A
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Withdrawn NCT02035319 - Effect of Laser Treatment on Capillary Malformations N/A
Completed NCT00830466 - A Randomized Trial to Study Combined Pulsed Dye Laser and Rapamycin Treatment of Port Wine Stain Birthmarks. Phase 1
Completed NCT00540371 - Dynamic Epidermal Cooling During Pulsed Dye Laser Treatment of Port Wine Stain Birthmark at High Fluences
Completed NCT01333553 - Monitoring the Response of Port Wine Stain Birthmarks to Laser Therapy With Wide-field Functional Imaging Technologies
Withdrawn NCT00580944 - Combined Alexandrite and Pulsed Dye Laser Treatment of Port Wine Stain Birthmarks Phase 1