PONV Clinical Trial
Official title:
Effect of Transcutaneous Electrical Acupoint Stimulation on Postoperative Nausea and Vomiting After Liver Surgery
Incidence of postoperative nausea and vomiting (PONV) could be high as 60% after liver surgery. Acupoint stimulation has been proved to decrease PONV. In this study, we will investigate the effect of transcutaneous electrical acupoint stimulation on incidence of PONV after liver surgery.
Status | Not yet recruiting |
Enrollment | 158 |
Est. completion date | May 30, 2023 |
Est. primary completion date | May 30, 2023 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 18 Years and older |
Eligibility | Inclusion Criteria: - age =18 years - scheduled for elective liver surgery under general anesthesia Exclusion Criteria: - body mass index less than 18 kg/m2 or higher than 30 kg/m2 - American Society of Anesthesiologists status higher than ? - patients with contraindication to transcutaneous electrical stimulation, including skin damage, infection or implantable electrical device - suspected or existed abuse of drug or alcohol - pregnant or breeding women - history of neurological or psychiatric disease |
Country | Name | City | State |
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n/a |
Lead Sponsor | Collaborator |
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Zhihong LU |
Lee A, Chan SK, Fan LT. Stimulation of the wrist acupuncture point PC6 for preventing postoperative nausea and vomiting. Cochrane Database Syst Rev. 2015 Nov 2;(11):CD003281. doi: 10.1002/14651858.CD003281.pub4. Review. — View Citation
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | incidence of nausea and vomiting by 24 hours after surgery | from end of surgery to 24 hours after surgery, in a total of 24 hours | ||
Secondary | incidence of nausea and vomiting by 48 hours after surgery | from end of surgery to 48 hours after surgery, in a total of 48 hours | ||
Secondary | incidence of nausea and vomiting in PACU (post-anesthesia care unit) | from end of surgery to discharge from PACU(post-anesthesia care unit), in an average of 30 minutes | ||
Secondary | score of nausea and vomiting by 24 hours after surgery | from end of surgery to 24 hours after surgery, in a total of 24 hours | ||
Secondary | score of nausea and vomiting by 48 hours after surgery | from end of surgery to 48 hours after surgery, in a total of 48 hours | ||
Secondary | score of nausea and vomiting in PACU(post-anesthesia care unit) | from end of surgery to discharge from PACU, in an average of 30 minutes | ||
Secondary | Quality of recovery score at 24 hours after surgery | from end of surgery to 24 hours after surgery, in a total of 24 hours | ||
Secondary | Quality of recovery score at 48 hours after surgery | from end of surgery to 48 hours after surgery, in a total of 48 hours | ||
Secondary | postoperative in-hospital stay | from end of surgery to discharge from hospital, in an average of 7 days | ||
Secondary | death by 6 months after surgery | from end of surgery to 6 months after surgery, in a total of 6 months |
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