Drug-drug Interaction Study

Status Completed

Clinical Trial Summary

This study evaluates drug-drug interactions between AT2220 (duvoglustat) and recombinant human alpha-glucosidase (rhGAA, also known as alglucosidase alfa) in participants with Pompe Disease.

Clinical Trial Description

This was a multi-center, international, open-label, two-period, fixed-sequence crossover study to evaluate the safety and pharmacokinetic effect of single ascending doses of duvoglustat on rhGAA administered 1 hour before initiation of a single rhGAA infusion. During Period 1, participants received a single intravenous infusion of rhGAA. During Period 2, each participant received a single oral dose of duvoglustat 1 hour prior to initiation of a single rhGAA infusion. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT01380743
Study type	Interventional
Source	Amicus Therapeutics
Contact
Status	Completed
Phase	Phase 2
Start date	October 31, 2011
Completion date	January 4, 2013

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See also
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