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Polyps clinical trials

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NCT ID: NCT06188871 Withdrawn - Clinical trials for Chronic Rhinosinusitis With Nasal Polyps

Early-onset Dupilumab Effects in CRSwNP

Start date: June 1, 2024
Phase: Phase 4
Study type: Interventional

While it is known that Dupilumab has profound effects in patients with CRSwNP, these are often seen months later after treatment initiation; however, in practice, patients often endorse feeling significantly better within days of their first injection. No studies have investigated the molecular basis for such an acute change. This study proposes that specific cytokine changes in phenotype in addition to microbiome and oscillometry effects play a synergistic role in producing this effect.

NCT ID: NCT04253990 Withdrawn - Colonic Polyps Clinical Trials

Efficacy and Safety of Precut-EMR for Resecting of Colonic Polyp

Start date: May 2016
Phase: N/A
Study type: Interventional

This study was attempted to determine the efficacy and complication of precut EMR comparing with convetional EMR for resecting of 10 ~ 20 mm colon polyp through prospective, randomized controlled trial.

NCT ID: NCT04158596 Withdrawn - Clinical trials for Chronic Rhinosinusitis Without Nasal Polyps

Safety and Efficacy of SDX-3101 for the Treatment of Chronic Rhinosinusitis Without Nasal Polyps (CRSsNP)

SDX-3101
Start date: June 1, 2020
Phase: N/A
Study type: Interventional

The purpose of this clinical trial is to assess the safety and efficacy of SDX-3101 for treatment of adult patients with chronic rhinosinusitis without nasal polyps (CRSsNP) by investigating a vibration pattern of SDX-3101 compared to a control

NCT ID: NCT03000868 Withdrawn - Colonic Polyps Clinical Trials

Comparison of Small Colorectal Polyp Removal Using Cold EMR With Hot EMR

Start date: December 1, 2016
Phase: N/A
Study type: Interventional

This study evaluates the efficacy of small colorectal polyp removal using cold endoscopic mucosal resection with hot endoscopic mucosal resection. Half of the participants will receive cold endoscopic mucosal resection, while the other half will receive hot endoscopic mucosal resection.

NCT ID: NCT02492685 Withdrawn - Gallbladder Polyp Clinical Trials

Quantificational Enhancement Pattern Analysis Using a Novel Software "Vuebox" of Contrast-enhanced Harmonic Endoscopic Ultrasonography for Differential Diagnosis Between Adenomas and Cholesterol Polyps

Start date: July 2015
Phase: N/A
Study type: Interventional

The investigators' study is a prospective study to evaluate the enhancement pattern of contrast-enhanced endoscopic ultrasonography and suggest the criterions for differential diagnosis between gallbladder polyps by using software program of quantitative analysis.

NCT ID: NCT02119273 Withdrawn - Clinical trials for Chronic Rhinosinusitis Without Nasal Polyps (CRSsNP)

Systemic Corticosteroids in the Perioperative Management of Chronic Rhinosinusitis Without Nasal Polyps (CRSsNP)

Start date: September 2014
Phase: Phase 4
Study type: Interventional

Oral corticosteroids are commonly utilized for the management of chronic rhinosinusitis with and without nasal polyps (CRSwNP and CRSsNP, respectively). Although strong evidence supports the benefit of routine and perioperative oral corticosteroids for CRSwNP, there is limited evidence to support their utility for CRSsNP. The investigators intend to perform a randomized, double blind, placebo controlled clinical trial to investigate the impact of steroids used within 2 weeks prior to surgery for CRSsNP. Patients with CRSsNP that present to the investigators office will be included if they have failed maximal medical management and have elected to undergo endoscopic sinus surgery (ESS) after July 1, 2014. The investigators hypothesis is that oral corticosteroids given 2 weeks prior to surgery will improve subjective and objective outcome measures.

NCT ID: NCT01369316 Withdrawn - Colonic Polyps Clinical Trials

Circumferential Submucosal Incision Endoscopic Mucosal Resection Versus Conventional Endoscopic Mucosal Resection of Colonic Polyps

CSIEMR
Start date: December 30, 2023
Phase: N/A
Study type: Interventional

That Circumferential Submucosal Incision Endoscopic Mucosal Resection (CSI-EMR) will be at least as safe but more effective than conventional EMR for injection assisted EMR of large laterally spreading tumour and sessile polyps of the colon.

NCT ID: NCT00841802 Withdrawn - Nasal Polyps Clinical Trials

Chronic Rhinosinusitis With or Without Nasal Polyps Steroid Study

Start date: July 2008
Phase: Phase 4
Study type: Interventional

This is a study to evaluate the cause of chronic sinus disease. Oral steroids have long been used in the treatment of inflammatory conditions including chronic sinusitis, asthma, and arthritis. However, it is not well known exactly which patients will benefit from steroids when used in the treatment of chronic sinusitis. For some doctors, it is common practice to use these medications prior to planned sinus surgery, to lessen the inflammation and possibly help the healing process. Other doctors feel oral steroids may not be helpful in this way, and there is no conclusive data as to whether this practice has a long term benefit.