Polynesian Bronchiectasis Clinical Trial
Official title:
Bronchi Dilation in Polynesian Patients: Monocentric Retrospective Study
| NCT number | NCT04798950 |
| Other study ID # | POLYDEB |
| Secondary ID | |
| Status | Not yet recruiting |
| Phase | |
| First received | |
| Last updated | |
| Start date | June 1, 2023 |
| Est. completion date | June 1, 2024 |
The study hypothesis is that dilations of idiopathic bronchi are particularly common in French Polynesia, and that there are arguments in favour of an underlying genetic factor. The study will retrieve retrospective data in the history of bronchial dilation, patients' personal and family history, microbiological and scannographic data, and the latest cardio respiratory checkup.
| Status | Not yet recruiting |
| Enrollment | 500 |
| Est. completion date | June 1, 2024 |
| Est. primary completion date | June 1, 2023 |
| Accepts healthy volunteers | No |
| Gender | All |
| Age group | 18 Years and older |
| Eligibility | Inclusion Criteria: - Polynesian patient - Patient with bronchial dilation followed by Centre hospitalier de Polynesie Francaise or patient with bonchial dilation no longer consulting in the hospital over the study period Jan 1, 2010 to Dec 31, 2020 Exclusion Criteria: - Expressed refusal to participate in the study for patients undergoing follow-up |
| Country | Name | City | State |
|---|---|---|---|
| n/a | |||
| Lead Sponsor | Collaborator |
|---|---|
| Centre Hospitalier Intercommunal Creteil |
| Type | Measure | Description | Time frame | Safety issue |
|---|---|---|---|---|
| Primary | Describe the detailed phenotype of bronchi dilation in the Polynesian population | Clinical criteria: age of onset, personal or family history, smoking Changes in respiratory function
Infectious complications: types of bronchial colonization (bacterial, mycobacterial and mycological) Scantographic aspect: Appearance of bronchectasis: cylindrical, varicose orcious, cystic Distributions: LSD, LM, LID, LSG, LIG |
Day 1 | |
| Secondary | Highlighting indirect arguments for a genetic cause | Age of onset of symptoms, frequency of so-called "idiopathic" bronchi dilatation, frequency of inbreeding, familial history | Day 1 |