Well-Formulated Ketogenic Diet Polycystic Kidney Disease

Polycystic Kidney Disease Clinical Trial

Official title: Feasibility and Efficacy of a Well-Formulated Ketogenic Diet in Delaying Progression of Polycystic Kidney Disease in Patients at Risk for Rapid Progression

Status Recruiting

Clinical Trial Summary

This is a prospective study to determine ketogenic diet effect on htTKV, GFR, microalbuminuria. This is a single-center study of 20 patients with ADPKD and deemed high risk for progression to ESRD. This determined by combination of features of ADPKD and htTKV as assessed by prior computed tomography (CT) or MRI. Patients will be recruited from the Polycystic Kidney Disease (PKD) Clinic at Ohio State University Wexner Medical Center. Enrolled patients will have MRI for htTKV, urinary studies, blood tests at baseline, 6 months, and 52 weeks. Blood for GFR will be assessed three times over the course of the study including baseline, 6 months, and 1 year. Participants will follow ketogenic diet for 52 weeks. Investigatory diet team will manage the ketogenic diet.

Clinical Trial Description

n/a

Related Conditions & MeSH terms

• Kidney Diseases
• Polycystic Kidney Disease
• Polycystic Kidney Diseases

• NCT number: NCT06325644
• Study type: Interventional
• Source: Ohio State University
• Contact: Madison L Kackley, PhD
• Phone: 6142479650
• Email: kackley.19@osu.edu
• Status: Recruiting
• Phase: N/A
• Start date: June 1, 2024
• Completion date: April 1, 2027