Clinical Trials Logo
  1. Home
  2. Pollution; Exposure
  3. NCT04068389
  4. Details
NCT04068389 Clinical Trial

Ultrafine Particles and Fetal Contamination

Pollution; Exposure Clinical Trial

— FOETOPUF  

Official title:
Study of the Permeability of Atmospheric Particles Placenta (Fine and Ultrafine Particles): Analysis of Fetal Retention

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT04068389
Other study ID # CHUBX 2008/04
Secondary ID
Status Completed
Phase
First received
Last updated
Start date December 22, 2009
Est. completion date November 9, 2012

Study information
Verified date August 2019
Source University Hospital, Bordeaux
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

The objective of this study is to evaluate the transplacental passage of fine and ultrafine particles (nanoparticles) inhaled by the mother.

Description:

Epidemiological studies have demonstrated the harmful effects of particulate air pollution on the progress of pregnancy and postnatal health.

Experimental studies have suggested the transplacental passage of asbestos fibers, but despite the strong growth in the use and production of fine and ultrafine particles, no study has examined the permeability of the placenta to these compounds or the exposures fetuses that may result.

The objective of this study is to evaluate the transplacental passage of fine and ultrafine particles (nanoparticles) inhaled by the mother.

Recruitment information / eligibility
Status Completed
Enrollment 62
Est. completion date November 9, 2012
Est. primary completion date November 9, 2012
Accepts healthy volunteers
Gender Female
Age group N/A and older
Eligibility Inclusion Criteria:

- All women volunteers for whom a medical termination of pregnancy is proposed for a fetus older than 22 weeks (weight over 500g).

Exclusion Criteria:

- Refusal of participation of the patient.

- Fetus with malformation syndrome affecting pulmonary perfusion.

Study Design

Related Conditions & MeSH terms

Intervention

Procedure:
• Pulmonary Tissue Collection
Pulmonary Tissue Collection

Locations
Country Name City State
n/a

Sponsors (1)
Lead Sponsor Collaborator
University Hospital, Bordeaux

Outcome
Type Measure Description Time frame Safety issue
Primary Presence of fine particles in fetal lung samples yes/no Analysis in electron microscopy At the screening
See also
  Status Clinical Trial Phase
Not yet recruiting NCT05105386 - The Impact of Synergies of Indoor Air Pollutants on Childhood Health and Wellbeing
Not yet recruiting NCT06074939 - FRESHAIR4Life: Building the Case for Action
Active, not recruiting NCT03376152 - Rural China Electric Kettle Promotion Program N/A
Completed NCT03969459 - Impact of Exposure to Persistent Organic Pollutants During Pregnancy on the Composition of Breast Milk and Consequences on the Newborn
Completed NCT04464720 - AIM to Improve Asthma: Airflow Improvements During Meal-Prep N/A
Enrolling by invitation NCT05724082 - The Effect of Household Air Pollution on Lung Function Growth in Infants With Pneumonia in Sub-Saharan Africa N/A
Recruiting NCT04821752 - Environmental Toxicants Avoidance Study N/A
Active, not recruiting NCT04695093 - Children's Health in London and Luton (CHILL)
Recruiting NCT04854187 - The Effect of Personal Protective Aids on Hypertension and Diabetes in People Exposed to High Levels of Air Pollution N/A
Not yet recruiting NCT04898439 - GReen And Healthy Schools N/A
Recruiting NCT04902989 - Environmental Pollutants and Their Effects on Respiratory Allergy
Completed NCT03894995 - Optimizing Ventilation to Improve Health N/A
Recruiting NCT05395663 - Scalability of a Home Health Navigator Program to Reduce Arsenic, Nitrate, and Lead in Private Well Water N/A
Not yet recruiting NCT06386055 - Air Pollution and Physical Activity: A Randomized Controlled Trial N/A
Completed NCT03552198 - Improving the Behavioural Impact of Air Quality Alerts N/A
Recruiting NCT05618769 - Towards Life-Long Healthy Lungs: A Multidisciplinary Follow-up Framework for Preterm Infants N/A
Enrolling by invitation NCT05368493 - Air Pollution and Development in the Boricua Youth Study N/A
Suspended NCT04013256 - Controlled Exposure of Healthy Nonsmokers to Secondhand and Thirdhand Cigarette Smoke N/A
Active, not recruiting NCT04353232 - Impact of Lifetime Exposure to Air and Noise Pollution on Cardiovascular Disease and Mortality - the AIRCARD Study.
Completed NCT03904875 - Air Pollution and COPD Exacerbation