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Clinical Trial Summary

The purpose of this study is to determine whether intrapleural treatment with Dornase alfa plus Urokinase improves clinical outcome compared to Urokinase alone in children with complicated parapneumonic effusions


Clinical Trial Description

n/a


Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Treatment


Related Conditions & MeSH terms


NCT number NCT00502632
Study type Interventional
Source Azienda Ospedaliera di Padova
Contact PierGiorgio Gamba, MD
Phone +39 049 821 3683
Email piergiorgio.gamba@unipd.it
Status Recruiting
Phase Phase 2/Phase 3
Start date October 2007
Completion date October 2009

See also
  Status Clinical Trial Phase
Recruiting NCT04095676 - VATS Surgery Compared to Drainage in the Treatment of Pleural Empyema N/A
Completed NCT01011881 - Procalcitonin in Pleural Pleuritis N/A
Terminated NCT00234208 - Early Medical Thoracoscopy Versus Simple Chest Tube Drainage in Complicated Parapneumonic Effusion and Pleural Empyema Phase 3
Active, not recruiting NCT05077111 - A Comparative Study Between Regional Anesthesia in Thoracoscopes and the Conventional General Anesthesia Phase 4
Completed NCT01717742 - Intrapleural DNase and Tissue Plasminogen Activator in Pediatric Empyema (DTPA Trial) Phase 3