Pleural Effusion Clinical Trial
Official title:
Randomized Study of Thoracoscopic Talc Pleurodesis Performed by Thoracic Epidural or General Anesthesia
Video-assisted thoracoscopic surgery (VATS) talc pleurodesis is often carried out in
patients with malignant recurrent pleural effusion to relieve symptoms and prevent
recurrence.
General anesthesia and one lung ventilation is the standard type of anesthesia employed for
VATS although recently, thoracic epidural anesthesia (TEA) in awake spontaneously
ventilating patients is being increasingly employed to perform several cardio-thoracic
surgery procedures in an attempt of minimize operative risks and facilitate resumption of
daily-life activity.
The investigators have reasoned that for a simple and palliative procedure such as talc
pleurodesis in cancer patients is, use of general anesthesia and one-lung ventilation might
be considered a potential cause of morbidity and delayed recovery. The investigators have
also hypothesized TEA could be considered an optimal type of anesthesia in this setting
leading to a fast recovery a reduced overall workload in medical care.
In this single-center randomized study, the investigators have comparatively assessed the
impact of awake TEA versus general anesthesia and one-lung ventilation on comprehensive
results of VATS talc pleurodesis.
n/a
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind (Subject), Primary Purpose: Treatment
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