Platelet-rich Plasma Clinical Trial
Official title:
Evaluation of the Efficacy of Platelet-rich Plasma (PRP) on Advanced Endoscopic Resection Techniques
To avoid complications secondary to advanced endoscopic resection techniques (Endoscopic Mucosal Resection -EMR- or Endoscopic Submucosal Disection -ESD-) the endoscopists have to avoid deep thermal damage and increase mucosal healing. Platelet-rich plasma (PRP) has demonstrated efficacy in preclinical endoscopic resection models.
Background:To avoid complications secondary to advanced endoscopic resection techniques
(Endoscopic Mucosal Resection -EMR- or Endoscopic Submucosal Disection -ESD-) the
endoscopists have to avoid deep thermal damage and increase mucosal healing. Platelet-rich
plasma (PRP) has demonstrated efficacy in preclinical endoscopic resection models.
Aim: Evaluate the efficacy of PRP on participants submitted to advanced endoscopic resection
techniques: EMR or ESD.
Material and Methods: The investigators have evaluated a prospective clinical study. The
investigators have included 12 participants submitted to EMR or ESD. Patients were informed
and accepted to participate with a written consent. Prior to endoscopy PRP was obtained from
autologous blood with a comercial kit. Submucosal injection with PRP were performed prior to
resection. Resection was performed with standard technique. Participants were followed-up
after the procedure.
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