Clinical Trials Logo
  1. Home
  2. Placebo
  3. NCT05007561

Understanding How Opioids Affect the Experiential and Neural Signatures of Social Experiences

Placebo Clinical Trial

Official title:
Understanding How Opioids Affect the Experiential and Neural Signatures of Social Experiences

Clinical Trial Summary

The study is a randomized, placebo-controlled design with the opioid antagonist, oral naltrexone. Following random assignment, participants will take 50mg of naltrexone or placebo once a day for 7 days. On days 1 - 7, participants complete reports of their feelings of social connection and mood in order to assess more naturalistic feelings in response to opportunities for social connection outside of the laboratory setting. Additionally, at the end of each day, they complete a physical symptoms questionnaire. On the 7th day, participants will come to the SDSU MRI scanning facility to complete tasks designed to elicit feelings of social connection in the fMRI scanner. After the scan, feelings in response to the scanner tasks will be collected.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05007561
Study type Interventional
Source San Diego State University
Contact Tristen Inagaki, PhD
Phone 6195941058
Email tinagaki@sdsu.edu
Status Recruiting
Phase Early Phase 1
Start date November 16, 2021
Completion date July 2026
View Details
See also
  Status Clinical Trial Phase
Completed NCT04852315 - Acute Caffeine Ingestion on Futsal Performance N/A
Completed NCT05427409 - Ingestion of Beta-alanine Effects in Well-trained Tennis Players N/A
Completed NCT05425563 - Effects of Expectations on Negative Affect, Perceived Cognitive Effort, and Pain N/A
Recruiting NCT04851301 - Neural Mechanisms of Immersive Virtual Reality in Chronic Pain Phase 1/Phase 2
Recruiting NCT03897998 - Neural Correlates of Hypoalgesia Driven by Observation Phase 2
Completed NCT04359147 - The Role of Stress Neuromodulators in Decision Making Under Risk and Selective Attention to Threat N/A
Recruiting NCT05145764 - Suvorexant as an Adjunct to Buprenorphine in Persons Who Use Fentanyl Phase 2
Completed NCT01167478 - Neurophysiological Reserve With Caffeine Manipulation N/A
Completed NCT05337527 - Neuromuscular Responses to Acute Beetroot Ingestion in Women Older Adults N/A
Terminated NCT01656577 - Pexacerfont for Stress-induced Food Craving Phase 0
Completed NCT04361968 - Combining Animal-assisted Intervention and Placebo-induced Analgesia N/A
Completed NCT03754062 - Pharmacological Modulation of Belief Salience Phase 1
Not yet recruiting NCT04317157 - Placebo Effects Investigated by Different Experimental Designs N/A
Completed NCT01361633 - The Cognitive Enhancing Effects of D-Cycloserine Among Non-Demented Elderly Phase 2
Completed NCT05209126 - Impact of Beetroot Juice Ingestion on Female Rugby Performance N/A
Completed NCT05521347 - Caffeine Supplementation Improves the Cognitive Abilities and Shooting Performance of Trained E-sports Players N/A
Completed NCT04975360 - Delayed-release Bedtime Caffeine and Sleep Inertia Symptoms Immediately Upon Awakening N/A
Completed NCT04671043 - Caffeine Ingestion to Counter the Exercise-mediated Fall in Glycaemia in Type 1 Diabetes N/A
Completed NCT01011465 - The Biology of Resilience N/A
Completed NCT05805540 - Effects on CK, RPE, VAS Scale and Physical Performance of Three Recovery Methods in Elite Basketball Players N/A