Pituitary Tumor Clinical Trial
Official title:
Nasal Outcomes Using Saline Irrigations After Endonasal Pituitary Surgery - The NOSE Trial
This is a prospective, single-blinded, multicenter study evaluating the benefit of sinonasal irrigations following endoscopic pituitary surgery. The goal of this study is to create practice changing guidelines with objective data highlighting the importance of irrigations on postoperative outcomes for pituitary surgery.
This prospective study, coupled with the results of the recent POET study evaluating the role of antibiotics in postoperative outcomes for pituitary surgery, will guide physicians in the optimal management of patients following endoscopic pituitary surgery. The investigator group has an established record of completing multicenter studies (e.g., POET, TRANSPHER) that have influenced clinical practice guidelines, raised the profile of Barrow in the pituitary and skull base community, and resulted in numerous peer-reviewed publications and awards. ;
Status | Clinical Trial | Phase | |
---|---|---|---|
Not yet recruiting |
NCT04529356 -
The TMS Treatment for Postoperative Headache in GH Tumor
|
N/A | |
Completed |
NCT03363126 -
Visual Outcome After Transsphenoidal Surgery for Pituitary Macroadenoma
|
N/A | |
Completed |
NCT04212793 -
Detection of PitNET Tissue During TSS Using Bevacizumab-800CW
|
Phase 1 | |
Recruiting |
NCT03309319 -
A Pilot Study of Rosiglitazone in the Treatment of GH Secreting Pituitary Adenomas
|
N/A | |
Terminated |
NCT04106531 -
Validation of a Quality of Life Metric "Prolac-10"
|
||
Recruiting |
NCT03719781 -
Postoperative Cognitive Dysfunction in Patients Undergoing Pituitary Removal Surgery
|
||
Recruiting |
NCT01556230 -
Prospective Study of Clinically Nonfunctioning Pituitary Adenomas
|
||
Recruiting |
NCT03132259 -
Comparative Low and High Dose of Dexmedethomidine in Pituitary Tumor Removal by Transphenoid Approach
|
Phase 4 | |
Recruiting |
NCT01368133 -
The Observational Study of Growth Hormone-secreting Pituitary Tumors
|
N/A | |
Withdrawn |
NCT04863339 -
Tranexamic Acid for Blood Loss Minimization in Endoscopic Pituitary Surgery
|
Phase 2 | |
Terminated |
NCT00646308 -
Assessment of Cardiovascular Risk Markers in Growth Hormone Deficient Patients With Nonsecreting Pituitary Adenomas
|
N/A | |
Recruiting |
NCT00852501 -
Characterization of Receptors in Non-functioning Pituitary Macroadenomas
|
Phase 4 | |
Completed |
NCT03465423 -
Comparison of Propofol Requirement Between Patients With Pituitary Somatotroph Tumor and With Nonfunctioning Pituitary Tumor in Transsphenoidal Pituitary Surgery Under Total Intravenous Anesthesia
|
||
Recruiting |
NCT03474601 -
Seoul National University Pituitary Disease Cohort Study
|
||
Recruiting |
NCT05139277 -
Evaluation of the CONVIVO System
|
N/A | |
Active, not recruiting |
NCT03636568 -
Hyponatremia Study (Delayed Hyponatremia After Pituitary Surgery)
|
N/A | |
Completed |
NCT02813044 -
Effects of Total Intravenous Anesthesia With Propofol-remifentanil Versus Inhalational Anesthesia With Sevoflurane on Quality of Recovery in Patients Undergoing Transsphenoidal Surgery for Pituitary Tumor
|
N/A | |
Recruiting |
NCT03973450 -
Epidemiology of Pituitary Tumours: Prevalence of Associated Neoplasia
|
||
Active, not recruiting |
NCT04042753 -
Nivolumab and Ipilimumab in People With Aggressive Pituitary Tumors
|
Phase 2 | |
Recruiting |
NCT04018963 -
The Impact of Endoscopic Pituitary Surgery on Nasal Function
|