Clinical Trials Logo

Clinical Trial Summary

This randomized controlled trial study aims at investigating the efficacy and safety of topical antioxidants in treatment of a cohort of non-elderly volunteers with photoaged skin.


Clinical Trial Description

•Sample size calculation: The sample size was assessed prospectively using Openepi version 3.01 to provide a 80% power to detect a 40-50% difference before and after treatment using either topical antioxidants or retinoids with a significance level of 0.05 (based on the results of a previous clinical trial). Assuming 10% dropout, 30 patients will be recruited in each treatment group. •Statistical analysis: Data will be collected and recorded on excel data sheet. Data will be tested for normality. Quantitative data will be represented as mean and standard deviation, or median and interquartile range. Qualitative data will be presented as number and percentage. The relevant statistical method will be used for comparison. P value will be considered statistically significant if it is less than 0.05 ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04835259
Study type Interventional
Source Sohag University
Contact esraa ismail
Phone 00201000509636
Email esraasalah123@yahoo.com
Status Not yet recruiting
Phase N/A
Start date April 2021
Completion date June 2022

See also
  Status Clinical Trial Phase
Completed NCT05271136 - A Clinical Study to Evaluate the Efficacy of an Anti-Aging Serum N/A
Completed NCT05514782 - A Clinical Study to Evaluate the Long-Term Efficacy and Tolerability of a Daily Anti-Aging Daily Serum N/A
Completed NCT04911374 - An Open-Label Clinical Study to Evaluate the Efficacy of a Face Cream and Eye Cream N/A
Completed NCT04586816 - Randomized, Double-Blind Evaluation of Maple Leaf Extract (Maplifa) for Photoaging N/A
Completed NCT05039723 - Xeomin, Radiesse, and Belotero Facial/Neck Rejuvenational Phase 4
Not yet recruiting NCT05004909 - Effectivity of 1 Finger Tip Unit Compared to 2 Finger Tip Units 0.05% Tretinoin Cream N/A
Completed NCT06366503 - Evaluating Procedure Pairing of a Post-Procedure Cream Versus a Comparator in Patients Treated With Fractional Ablative CO2 Laser for Facial Rejuvenation N/A
Completed NCT05027282 - Safety and Effectiveness of the CLEAR + BRILLIANT TOUCH(R) Diode Laser 1440-nm and 1927-nm Combination Wavelength Treatment N/A
Not yet recruiting NCT06096649 - The Effects of Zinc Di-(Dibutyryl Lisinate) on Skin Health and the Skin Microbiome in Photoaged Skin N/A
Completed NCT03661697 - Combination Versus Laser Treatment Only N/A
Completed NCT03948945 - Efficacy and Safety of Profile HaloTM Mixed Fractional Laser on Treating of Facial and Neck Photoaging. N/A
Completed NCT06148558 - A Twelve Week Clinical Study to Evaluate the Efficacy and Tolerability of a Sunscreen Moisturizer SPF 50+ N/A
Enrolling by invitation NCT06188338 - A 56-day Clinical Study on Facial Skin Rejuvenation N/A
Recruiting NCT06195605 - Investigating Age Dependence of Fibroblast and Extracellular Matrix Responses to Cross-linked Hyaluronic Acid Filler in Human Skin N/A
Not yet recruiting NCT04869852 - Effects of Mango Intake on Skin Health and Gut Microbiome Changes in Postmenopausal Women N/A
Not yet recruiting NCT02126644 - The Efficacy and Safety of a Single 70% Glycolic Acid Peel With Vitamin C for the Treatment of Photoaging Phase 2
Active, not recruiting NCT01372566 - Effect of Platelet Rich Plasma on Photoaged Skin Phase 1/Phase 2
Unknown status NCT00842907 - Efficacy and Safety of Oral Isotretinoin for Cutaneous Photodamage Phase 2
Completed NCT03112863 - Comparison of the Cosmetic Effects of Bakuchiol and Retinol Early Phase 1
Recruiting NCT05386368 - RECELL to Promote Healing Following Carbon Dioxide (CO2) Laser Treatment in Cosmetic Patients Phase 4