Photoaging of Skin Clinical Trial
Official title:
The Effects of Autologous Platelet-Rich Plasma Cream on Photoaging and Chronological Skin Aging
Human skin undergoes some morphological changes with the effects of chronological aging and
photoaging, these are especially remarkable in the facial skin. Changes in pigmentation,
sallowness, deep wrinkling, laxity and elastosis are the main changes seen in photoaging and
chronologic aging of skin. With the increasing demand, it needs to provide new approach for
the prevention and treatment of these morphological changes.
Fibroblasts have a key role on skin aging. It is known that platelet rich plasma activates
the fibroblasts and increases the synthesis of collagen and other type of matrix components.
Because of these specialities, platelet rich plasma is thought to be effective on skin
aging.
Clinical evaluation of the patients will be done for five times during 3 months. 0th day (Basal), 7th day, 15th day, 45th day and 105th day. ;
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Double Blind (Subject, Caregiver), Primary Purpose: Treatment
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