Phosphorus and Calcium Disorders Clinical Trial
Official title:
Serum Calcium to Phosphorus (Ca/P) Ratio to Define Disorders of Ca-P Metabolism
BACKGROUND: Primary hyperparathyroidism (PHPT) is the third most common endocrine disorder.
The Ca/P ratio is an accurate tool to differentiate patients with PHPT (>3.5 if Ca and P are
expressed in mg/dl) from healthy subjects. The reliability of this index is based on the fact
that serum Ca and P are inversely related together. However, other disorders of the Ca-P
metabolism, such as hypophosphoremia (HypoP) not related to PHPT, might also impair the Ca/P
ratio.
OBJECTIVE: To validate the accuracy of Ca/P ratio in the diagnosis of Ca-P metabolism
disorders, including also patients with documented HypoP not related to PHPT.
METHODS: A single-center, retrospective, case-control study will be carried out.
Biochemical measurements will include parathormone (PTH), vitamin D, serum Ca and P, serum
albumin and creatinine.
n/a
Status | Clinical Trial | Phase | |
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Completed |
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