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Clinical Trial Details — Status: Completed

Administrative data

NCT number NCT00188019
Other study ID # PHRC 04-01
Secondary ID
Status Completed
Phase N/A
First received September 12, 2005
Last updated July 22, 2015
Start date November 2005
Est. completion date November 2013

Study information

Verified date July 2015
Source University Hospital, Angers
Contact n/a
Is FDA regulated No
Health authority France: Ministry of Health
Study type Interventional

Clinical Trial Summary

Hereditary paraganglioma -due to SDH (SDHD, SDHB, SDHC) germline mutations- causes paragangliomas and pheochromocytomas. Presymptomatic genetic testing should be offered to all first-degree relatives if an SDH mutation is detected in an index case with paraganglioma or pheochromocytoma. The main objective of our national clinical research project is to test different screening methods to detect presymptomatic tumors in order to establish guidelines for the work-up and the follow-up of SDH mutation carriers.


Recruitment information / eligibility

Status Completed
Enrollment 248
Est. completion date November 2013
Est. primary completion date November 2013
Accepts healthy volunteers No
Gender Both
Age group 6 Years and older
Eligibility Inclusion Criteria: identification of an SDH (SDHD, SDHD, SDHC) germline mutation

Study Design

Allocation: Non-Randomized, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Diagnostic


Related Conditions & MeSH terms


Intervention

Procedure:
diagnosis methods


Locations

Country Name City State
France Européen Georges Pompidou Hospital Paris

Sponsors (2)

Lead Sponsor Collaborator
University Hospital, Angers Assistance Publique - Hôpitaux de Paris

Country where clinical trial is conducted

France, 

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