Protein Requirements in Adults With Phenylketonuria (PKU)

Status Recruiting

Clinical Trial Summary

Phenylketonuria (PKU) is an inherited inborn error of phenylalanine (PHE) metabolism caused by decreased activity of phenylalanine hydroxylase (PAH) enzyme. Therefore, PHE accumulates in plasma leading to mental problems. Treatment is a phenylalanine-restricted diet with sufficient protein. However, the optimum protein requirements are still unknown and compliance with diet is not satisfactory in PKU adults. A Previously established technique called indicator amino acid oxidation (IAAO) will be used to determine protein requirements from amino acid based formula vs. glycomacropeptide (GMP) in adults with PKU (≥ 19y). This study will help treat adults with enough protein ensuring maintenance of health.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT03939052
Study type	Interventional
Source	University of British Columbia
Contact	Rajavel Elango, PhD
Phone	604-875-2000
Email	relango@bcchr.ubc.ca
Status	Recruiting
Phase	N/A
Start date	July 19, 2019
Completion date	May 2020

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See also
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