Pharyngitis Clinical Trial
Official title:
Best Assessment of Sore Throat and Antibiotic Prescribing
This project aims to investigate if an organisational change of patient flow away from medical practitioners can reduce unnecessary antibiotic prescribing in patients attending with a sore throat as the main complaint.
Today patients appear either at a PHC centre or at the Pharmacy. The Pharmacy may provide advice on analgesic or refer the patient to a PHC centre. At the PHC centre, the patient may first appear to the medical practitioner or a nurse pending on local routines. The current Swedish guideline recommends no antibiotics and no testing for patients with 0-2 Centor criteria. For patients with 3-4 Centor criteria the guideline recommends testing and only consider antibiotics if GAS is present. COVID-19 has gradually transformed from expressing itself as a severe lower respiratory tract infection to be more of an upper respiratory tract infection. Furthermore, COVID-19 is likely to transform from a pandemic to an endemic state with a low continuous incidence. Hence, in response to COVID-19 it seems crucial to identify to what extent the common sore throat is caused by the SARS-CoV-2. Furthermore, a large controlled clinical trial is required to sort out if patients attending with a sore throat as the main complaint are best managed by medical practitioners, nurses or pharmacists. This study aims to perform such a controlled clinical trial comparing the outcome of sore throat patients management by medical practitioner, nurses and pharmacists. This study also aims to investigate to what extent the SARS-CoV-2 virus is identified in these patients. ;
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT01453400 -
Evaluate the Time of Pain Relief of Fast Acting Aspirin Versus Acetaminophen in Subjects Diagnosed With Sore Throat Pain
|
Phase 3 | |
Completed |
NCT04016051 -
Acceptance of Clarithromycin in a Straw Compared to Syrup in Children With Upper Respiratory Tract Infections
|
Phase 3 | |
Recruiting |
NCT01681667 -
Tablet vs. Liquid Suspension Ibuprofen in the Relief of Pain
|
Phase 4 | |
Completed |
NCT00527852 -
Assessment of Flocked Swabs for the Identification of Group A Streptococcal Pharyngitis
|
N/A | |
Completed |
NCT02178293 -
Ketoprofen Lysine Salt as Mouthwash in Acute Phlogosis of the Pharyngeal Cavity Versus Benzidamine Hydrochloride
|
Phase 4 | |
Active, not recruiting |
NCT05127161 -
Broad Implementation of Outpatient Stewardship
|
N/A | |
Withdrawn |
NCT02535962 -
Probiotics and Corticosteroids for Treating Periodic Fever, Aphthous Stomatitis, Pharyngitis, Cervical Adenitis (PFAPA)
|
Phase 2 | |
Not yet recruiting |
NCT02252419 -
Combined Effect of Dexamethasone and Paracetamol for Postoperative Sore Throat
|
N/A | |
Completed |
NCT00798018 -
Effect of Intra-cuff Lidocaine and Tetracaine on Tracheal Tube-induced Emergence Phenomena
|
N/A | |
Completed |
NCT00535093 -
An Assessment of Rapid Streptococcal Tests in Community Clinics in Israel
|
N/A | |
Completed |
NCT00148499 -
Efficacy and Tolerability of Ambroxol Lozenge 20 mf in Relieving Pain of Sore Throat in Pat. With Acute/Viralpharyngitis
|
Phase 3 | |
Completed |
NCT00095368 -
APC-111 Once a Day (QD) for 7 Days vs. Penicillin Taken Four Times a Day (QID) for 10 Days in Patients With Strep Throat
|
Phase 3 | |
Recruiting |
NCT06027593 -
Using Electronically Derived Automated Reports of Appropriate Antibiotic Use to Inform Stewardship Interventions
|
N/A | |
Recruiting |
NCT03720301 -
The Use of Osteopathic Medical Manipulation to Decrease the Incidence and Severity of Post-Operative Sore Throat
|
N/A | |
Completed |
NCT01361399 -
Active and Placebo Controlled Study to Test the Efficacy and Safety of an Aspirin-Lidocaine Lozenge in the Symptomatic Treatment of Sore Throat Associated With a Common Cold
|
Phase 3 | |
Completed |
NCT01049334 -
A Study of Flurbiprofen 8.75 mg Lozenge in Patient With Pharyngitis
|
Phase 3 | |
Completed |
NCT01398696 -
Impact of Four Patient Information Leaflets (PIL) on Patient Behaviour
|
Phase 4 | |
Completed |
NCT01048866 -
A Study of Flurbiprofen 8.75 mg Lozenge in Patients With Pharyngitis
|
Phase 3 | |
Completed |
NCT00547391 -
Recurrent Throat Infections and Tonsillectomy
|
Phase 4 | |
Completed |
NCT00242281 -
APC-111 MP Tablet Once a Day vs.Penicillin VK Four Times a Day Both for 10 Days in Patients With Strep Throat
|
Phase 3 |