Pharyngitis Clinical Trial
Official title:
Tablet vs. Liquid Suspension Ibuprofen in the Relief of Pain
Ibuprofen (also known as Advil or Motrin) is a medication that is known to reduce pain. It is also known that ibuprofen levels in the blood rise higher and faster if the medication is taken in liquid suspension. This study will attempt to determine if ibuprofen suspended in a liquid works to relieve sore throat pain faster than pills of ibuprofen. It will also determine whether patients with sore throat prefer to take pill or liquid form of the medication.
Status | Recruiting |
Enrollment | 100 |
Est. completion date | May 2015 |
Est. primary completion date | May 2015 |
Accepts healthy volunteers | No |
Gender | Both |
Age group | 12 Years to 65 Years |
Eligibility |
Inclusion Criteria: - Age greater than 12 years and less than 65 years - Weight > 40 kg - a provider order for ibuprofen to address pharyngitis pain. - Initial Numeric Pain Score > 6 Exclusion Criteria: - Known allergy or hypersensitivity to aspirin or NSAIDs - Inability to swallow pills - Inability to carry out informed consent in English - Inability to complete a visual analog pain scale - A concomitant order for another class of analgesic - Use of analgesic within 8 hours - Known 3rd trimester pregnancy - Significant medical conditions where participation would pose an unnecessary barrier to ongoing care. - Those taking opioid medications for more than 3 days - Weight < 40 kg |
Allocation: Randomized, Endpoint Classification: Pharmacokinetics Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver), Primary Purpose: Treatment
Country | Name | City | State |
---|---|---|---|
United States | Albany Medical Center Emergency Department | Albany | New York |
Lead Sponsor | Collaborator |
---|---|
Albany Medical College |
United States,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Time of pain relief | Comparing liquid ibuprofen to tablet ibuprofen to determine which works faster to relieve sore throat pain. We will also determine whether patients with sore throat prefer to take pill or liquid form of medication. | 1 hour | No |
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