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Clinical Trial Summary

Tigecycline is a commonly used antibiotic in critically ill patients. The pharmacokinetics (PK) of tigecycline in intensive care unit (ICU) patients can be affected by severe pathophysiological changes so that standard dosing might not be adequate. At present, a number of studies have reported that ECMO will affect the PK of anti-infective drugs and lead to treatment failure. The purpose of this study was to describe the population PK of tigecycline in patients treated with ECMO and to evaluate the relationship between individual PK parameters and patient covariates.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT04724798
Study type Observational
Source Nanfang Hospital of Southern Medical University
Contact Yuan Zhang, doctor
Phone +8615626182275
Email m15626182275@163.com
Status Recruiting
Phase
Start date January 20, 2020
Completion date December 30, 2022

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